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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 155 documents. Results 1 - 10.

Mus musculus
Gene: ... define the functional anatomy of RAG- 1, we mutated all 86 conserved basic amino acids to alanine...Disease relevance of Rag1 The resolution of bacteremia coincided with an expansion and persistence... -/- mice conferred immunity to Rag1 -/- mice. Analysis of GF and conventionally raised Rag1 -/- mice... / Synonyms: RAG-1; Rag-1
Homo sapiens
Gene: ... protein inhibited the binding of the RAG1/ RAG2 complex to all the methylated CpG sites that were tested...Disease relevance of RAG1 Amorphic mutations in the recombination activating genes RAG1 and RAG2... autoimmune T cell clones responsible for the Omenn syndrome phenotype. Human RAG2, like RAG1... / Synonyms: RAG-1
MeSH term: ... activating genes 1 and 2( RAG1/ RAG2) or Artemis were found in some, but not all, patients with Omenn...High impact information on Genes, RAG- 1 CD19+ CD10+ human B lineage bone marrow cells were... activating gene( RAG- 1 ), and terminal deoxynucleotidyl transferase( TdT). After 13- 15 days, transcripts... / Synonyms: Gene, RAG-1; Genes, RAG 1; RAG 1 Genes
Danio rerio
Gene: ... High impact information on rag1 Artificial chromosome transgenesis reveals long- distance negative regulation of rag1 in zebrafish. Immigrants on the way to the thymus expressed c- myb and ikaros but not rag1... to the kidney. Also by day 4, rag1 transcripts are seen in the pancreas, an organ not previously associated... / Synonyms: RAG-1
Gallus gallus
Gene: ... High impact information on RAG1 Therefore, we have examined the potential role of the V( D) J recombination activating genes, RAG- 1 and RAG- 2, in regulating chicken Ig gene conversion. The single- copy RAG- 1 gene is found throughout higher vertebrates and consists of a single 3. 1- kb exon without...
Sus scrofa
Gene: ... Disease relevance of RAG- 1 In recipient RAG- 1 -/- mice, fatal EMCV disease occurred within 2 days...- 1 The RAG- 1 mRNA levels in the shark were analyzed using semi- quantitative PCR to reveal..., but resulted in detection of EMCV RNA in the brain of recipient RAG- 1 -/- mice, no viral RNA was detected...
MeSH term: ... and the expression pattern in tissues and cell lines indicate that RAG- 1 either activates or catalyzes the V( D) J... observed in a number of glioma, prostate, kidney and breast carcinoma cell lines or tumour specimens. All.... In parallel with IgG- induced elevations in intracellular cyclic AMP levels in the same cell line, all 20...
MeSH term: ... of the kidney, ureter, eye, ear and central nervous system. The recombination activating gene- 1( RAG- 1.... All four glycine transporters of the" GLYT family" also belong to the neurotransmitter superfamily... in the embryonic central nervous system and on all sensory axon pathways in the peripheral nervous system. Neurons...
MeSH term: ... - deficient Rag1 (-/-) mice, lineage- committed granulocyte- macrophage progenitors( GMPs) or bone marrow... by all gram- negative bacteria, activates macrophages to release cytokines that are potentially lethal...
MeSH term: ... of this hypothesis. The RAG- 1 transcript was found to be widespread in embryonic and postnatal neurons...


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