Your search matched a total of 60 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of SIRT1 Interestingly, the regulation of SIRT mRNAs was highly similar both... neurons. SIRT1 protects against microglia- dependent amyloid- beta toxicity through inhibiting NF- kappaB signaling. Tat and SIRT1 coimmunoprecipitate and synergistically activate the HIV promoter. DHT- induced... / Synonyms: hSIRT1
Mus musculus
Gene: ... Disease relevance of Sirt1 These results suggest that endogenous Sir2alpha plays an essential role... on Sirt1 We review Sir2, a factor linking genomic stability, metabolism, and aging. We report that Sir2... induced by Sir2alpha, and also enhances the p53 acetylation levels in vivo. Biological context of Sirt1...
Rattus norvegicus
Gene: ... High impact information on Sirt1_ predicted High- fat diet upregulated the forkhead transcription factor Foxo3a, and suppressed mitochondrial aconitase activity without affecting expression... peroxidation and apoptosis. Analytical, diagnostic and therapeutic context of Sirt1_ predicted In yeast...
Gallus gallus
Gene: ... High impact information on SIRT1 Cells rendered doubly deficient in SIRT1 and SIRT2 exhibited the same levels of IR and cisplatin sensitivity as SIRT1 -/- cells. Our results indicate that SIRT1... of SIRT1 SIRT1 -/- cells appeared to be defective neither in DNA double strand break repair nor in G2/ M...
Chemical compound: ... longevity and improves glucose homeostasis in mice by stimulating the Sirt1- mediated deacetylation...
Chemical compound: ... Metabolic Disease by Activating SIRT1 and PGC- 1alpha. At concentrations( approximately 3- 10 micro... in Alzheimer' s disease. In a mouse model of Huntington' s disease, resveratrol- induced SIRT1 was found... by stimulating the Sirt1- mediated deacetylation of the transcriptional coactivator PGC- 1alpha. We tested...
MeSH term: ... and epigenetic silencing of HIC1, we speculate that the resultant upregulation of SIRT1 may be a double- edged..., this upregulation in homeostatic regulatory mechanisms is not sufficient as these are unable to neutralize all...
MeSH term: ... consumption is decreased. In PC12 cells, increased expression of the NAD- dependent deacetylase SIRT1 reduces...
Gallus gallus
Gene: ... High impact information on SIRT2 Cells rendered doubly deficient in SIRT1 and SIRT2 exhibited the same levels of IR and cisplatin sensitivity as SIRT1 -/- cells. Our results indicate that SIRT1... with chemical compounds Furthermore, both SIRT1- and SIRT2- deficient cells were more sensitive to pro...
MeSH term: ... . Beads preferentially deacetylated by SIRT1 were biotinylated and labeled with streptavidin- coated...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann