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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 67 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of TGFBR2 Heterozygous TGFBR2 mutations in Marfan syndrome. The type II transforming growth factor( TGF )- beta receptor gene( TGFBR2) is often mutated in nucleotide repeat sequences... unmatched sets of 17 primary and 17 recurrent breast tumor samples for mutations in TGFBR2, restricted...
Mus musculus
Gene: ... Disease relevance of Tgfbr2 Loss of Tgfbr2 in the mammary epithelium results in lobular- alveolar hyperplasia in the developing mammary gland and increased apoptosis. Cleft palate in Tgfbr2 mutant mice... the functional role of TGFBR2 inactivation in the multistep progression sequence of colon cancer, we generated...
Rattus norvegicus
Gene: ... Disease relevance of Tgfbr2 We evaluated the correlation of arterial proliferation with plasma... on Tgfbr2 We have previously shown that transforming growth factor beta 1( TGF- beta 1) receptor and TGF... sympathetic ganglia express TGFbeta- type II receptor. Biological context of Tgfbr2 RNA blot hybridization... / Synonyms: Tgfbr2T
Xenopus laevis
Gene: Synonyms: tgfbr2; tgfbr2-A
MeSH term: ... palate in Tgfbr2 mutant mice results from a cell proliferation defect within the CNC- derived palatal... to epithelial tumorigenesis. Our results show that all posterior limb mesenchyme cells, as well as the ectoderm...
MeSH term: ... ; no mutations were found. Somatic alterations of the TGF- beta type II receptor gene( TGFBR2) were identified... inhibitors. Here we report that although all nonsense and frameshift mutations that cause premature... was found. All externally, suppressible frameshift mutations occur in glycine and proline codons to produce...
MeSH term: ... in TGFBR2, a putative tumor- suppressor gene implicated in several malignancies, are also associated... patients with connective tissue disease. All mammals produce heparin, a negatively charged... with tretinoin( all- trans- retinoic acid) inhibited the induction of matrix metalloproteinase proteins...
Homo sapiens
Gene: ... - beta circulating levels. We hypothesized that functional genetic variants in TGFB1 and TGFBR2... polymorphisms in TGFB1 and G- 875A variant in TGFBR2, using the primer- introduced restriction analysis( PIRA... production, and eosinophilia. These cells recognize antigen as do all T cells, but they secrete...
Chemical compound: ... that loss of TGFBR2 in colon epithelial cells promotes the establishment and progression of AOM- induced colon neoplasms, providing evidence from an in vivo model system that TGFBR2 is a tumor suppressor gene... reduction of ACF formation. By mating Fabpl( 4xat- 132) Cre mice with Tgfbr2( flx/ flx) mice, we have...
MeSH term: ... codon upstream of the bHLH domain. Conditional inactivation of Tgfbr2 in cranial neural crest causes... proliferation in the dura mater, consequently resulting in calvaria agenesis. We show that mice with Tgfbr2...

 

 
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