Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CCRIS 920 9H-fluorene-2,7-diamine

Synonyms: CHEMBL81945, SureCN123584, D17106_ALDRICH, AG-F-79305, AG-L-23509, ...

Gebran, S.J. et al., Yamashita, R.I. et al., Kaiho, S. et al.

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High impact information on NSC12277

A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene [1].
The assay uses red blood cells (RBC) as target cells and relies on the specific oxidation of 2,7-diaminofluorene (DAF) by the pseudoperoxidase activity of hemoglobin (Hb) [1].
Benzidine derivatives, especially 2,7-diaminofluorene and benzidine, accelerated the cleavage of a plasmid DNA (form I) under weakly acidic conditions at 37 degrees C. The acceleration was not inhibited by EDTA, superoxide dismutase, catalase, or hydroxyl radical scavengers [2].

Analytical, diagnostic and therapeutic context of NSC12277

Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation [3].

References

A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene. Gebran, S.J., Romano, E.L., Pons, H.A., Cariani, L., Soyano, A.N. J. Immunol. Methods (1992) [Pubmed]
Acceleration of DNA cleavage by benzidine derivatives under weakly acidic conditions. Yamashita, R.I., Tomimoto, T., Nakamura, Y. Chem. Pharm. Bull. (1994) [Pubmed]
Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation. Kaiho, S., Mizuno, K. Anal. Biochem. (1985) [Pubmed]

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