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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Colorimetry

  • A rapid method of reflectance colorimetry was used to quantitate growth and acid production (as determined by the colour change in bromcresol purple) of Lactobacillus curvatus, added to a meat product model system [1].
  • Two rapid screening methods [the TECRA Listeria Visual Immunoassay (LIS-VIS) kit, an AOAC-approved 48 h visual test, which detects Listeria through colorimetry, and BCM Listeria isolation and differentiation plating agar] were used to screen U.S. Food and Drug Administration-regulated commodities for the presence of Listeria spp [2].
  • Cloning and expression of the nucleotide binding domain of the human MDR1 gene in Escherichia coli was established, and by using colorimetry to examine the activity of ATPase to hydrolyse ATP, the ATPase activity of target nucleotide binding domain protein was determined [3].
  • Distributions of phenol in fatal poisonings have been reported, but colorimetry was used as the analytical method and it cannot exclude the interference of other phenolic compounds [4].
  • Experiments have confirmed that MTT-formazan colorimetry in its simplest form (incubation of intact worms with MTT and direct visualisation of any formazan formed) can be readily applied to several species of filariae including Onchocerca volvulus [5].

High impact information on Colorimetry

  • At the end of treatment, colorimetry demonstrated a 40 percent lightening of the lesions toward normal skin color in the tretinoin-treated lesions, as compared with an 18 percent lightening in vehicle-treated lesions (P = 0.05) [6].
  • The same culture dishes were assessed by image analysis and by formazan colorimetry for purposes of comparing multiple methods of measuring growth as well as growth inhibition [7].
  • Malondialdehyde, a byproduct of thromboxane synthesis, was measured by colorimetry [8].
  • We have also compared under the same conditions the degradation products of NO, nitrite, and nitrate in the renal cortex and medulla using in vivo microdialysis combined with microtiter plate colorimetry [9].
  • Each serum sample was analyzed for total testosterone by RIA, SHBG-binding capacity was determined by protein precipitation with 50% saturated (NH4)2SO4, and albumin was measured by colorimetry [10].

Biological context of Colorimetry


Anatomical context of Colorimetry


Associations of Colorimetry with chemical compounds


Gene context of Colorimetry


Analytical, diagnostic and therapeutic context of Colorimetry


  1. Partial characterisation of pediocin PO2 and comparison with nisin for biopreservation of meat products. Coventry, M.J., Muirhead, K., Hickey, M.W. Int. J. Food Microbiol. (1995) [Pubmed]
  2. Comparison of visual immunoassay and chromogenic culture medium for the presence of Listeria spp. in foods. Istafanos, P., James, L., Hunt, J. Journal of AOAC International. (2002) [Pubmed]
  3. Reversal of cancer multidrug resistance by green tea polyphenols. Mei, Y., Qian, F., Wei, D., Liu, J. J. Pharm. Pharmacol. (2004) [Pubmed]
  4. Distribution of phenol in a fatal poisoning case determined by gas chromatography/mass spectrometry. Tanaka, T., Kasai, K., Kita, T., Tanaka, N. J. Forensic Sci. (1998) [Pubmed]
  5. The further application of MTT-formazan colorimetry to studies on filarial worm viability. Comley, J.C., Townson, S., Rees, M.J., Dobinson, A. Trop. Med. Parasitol. (1989) [Pubmed]
  6. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients. Bulengo-Ransby, S.M., Griffiths, C.E., Kimbrough-Green, C.K., Finkel, L.J., Hamilton, T.A., Ellis, C.N., Voorhees, J.J. N. Engl. J. Med. (1993) [Pubmed]
  7. Morphometric and colorimetric analyses of human tumor cell line growth and drug sensitivity in soft agar culture. Alley, M.C., Pacula-Cox, C.M., Hursey, M.L., Rubinstein, L.R., Boyd, M.R. Cancer Res. (1991) [Pubmed]
  8. The role of platelet aggregation and release in fragment D-induced pulmonary dysfunction. Manwaring, D., Curreri, P.W. Ann. Surg. (1980) [Pubmed]
  9. Nitric oxide in renal cortex and medulla. An in vivo microdialysis study. Zou, A.P., Cowley, A.W. Hypertension (1997) [Pubmed]
  10. Non-sex hormone-binding globulin-bound testosterone as a marker for hyperandrogenism. Cumming, D.C., Wall, S.R. J. Clin. Endocrinol. Metab. (1985) [Pubmed]
  11. A study of thyroglobulin and peroxidase activity in the thyroid tissue of patients with non-endemic non-toxic nodular goitre. Mories, T., Miralles, J.M., Reglero, A., Felipe, S., Corrales, J.J., Garcia, L.C. Clin. Sci. (1991) [Pubmed]
  12. Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin. Yu, Y., Sun, P., Sun, L.C., Liu, G.Y., Chen, G.H., Shang, L.H., Wu, H.B., Hu, J., Li, Y., Mao, Y.L., Sui, G.J., Sun, X.W. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  13. Influence of methodology on glycosylated hemoglobin values in Nigerian subjects with sickle cell hemoglobinopathy. Ohwovoriole, A.E., Kuti, J.A., Johnson, T.O. Ann. Clin. Lab. Sci. (1984) [Pubmed]
  14. Tracking the elusive antiestrogenic effect of melatonin: a new methodological approach. Girgert, R., Bartsch, C., Hill, S.M., Kreienberg, R., Hanf, V. Neuro Endocrinol. Lett. (2003) [Pubmed]
  15. Chemo-radionuclide therapy for thyroid cancer: initial experimental study with cultured cells. Misaki, T., Iwata, M., Iida, Y., Kasagi, K., Konishi, J. Annals of nuclear medicine. (2002) [Pubmed]
  16. Determination of IL-2 and cytotoxicity of killer cells in MTT colorimetry. Shen, G.X., Zhu, H.F., Zhang, Y., Wang, X.L., Shao, J.F., Yang, D.F. J. Tongji Med. Univ. (1993) [Pubmed]
  17. Studies on the apoproteins of the major lipoprotein of the yolk of hen's eggs. V. Protein sulfhydryl groups: accessibility in the lipoprotein and the effect of temperature. Nguyen, T.H., Burley, R.W. Aust. J. Biol. Sci. (1984) [Pubmed]
  18. Effects of high temperature and noise on erythrocyte membrane ATPase activity in pilots during flight. Qin, S.Z., Yu, Q.F., Ma, G.X., Hao, W.W., Li, M.G., Zhao, H. Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering. (1999) [Pubmed]
  19. Inaccuracy in measuring glycated albumin concentration by thiobarbituric acid colorimetry and by boronate chromatography. Johnson, R.N., Baker, J.R. Clin. Chem. (1988) [Pubmed]
  20. Phloroglucinol-based colorimetry of xylose in plasma and urine compared with a specific gas-chromatographic procedure. Johnson, S.L., Bliss, M., Mayersohn, M., Conrad, K.A. Clin. Chem. (1984) [Pubmed]
  21. Amperometric determination of total cholesterol at gold electrodes covalently modified with cholesterol oxidase and cholesterol esterase with use of thionin as an electron mediator. Nakaminami, T., Ito, S., Kuwabata, S., Yoneyama, H. Anal. Chem. (1999) [Pubmed]
  22. Dichlorobenzoquinone chloroimine colorimetry of uric acid in urine. Miller, P., Oberholzer, V. Clin. Chem. (1990) [Pubmed]
  23. Simpler colorimetry of serum acetaminophen. Gupta, R.N. Clin. Chem. (1982) [Pubmed]
  24. Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes. Yang, L.Q., Yu, W.F., Cao, Y.F., Gong, B., Chang, Q., Yang, G.S. World J. Gastroenterol. (2003) [Pubmed]
  25. Short- and long-term effects of ibandronate treatment on bone turnover in Paget disease of bone. Woitge, H.W., Oberwittler, H., Heichel, S., Grauer, A., Ziegler, R., Seibel, M.J. Clin. Chem. (2000) [Pubmed]
  26. Colorimetry of diaphorase in commercial preparations and clinical chemical reagents by use of tetrazolium salts. Gella, F.J., Olivella, M.T., Pegueroles, F., Gener, J. Clin. Chem. (1981) [Pubmed]
  27. Direct micromethod for colorimetry of serum ornithine carbamoyltransferase activity, with use of a linear standard curve. Vassef, A.A. Clin. Chem. (1978) [Pubmed]
  28. Colorimetry and constant-potential coulometry determinations of transferrin-bound iron, total iron-binding capacity, and total iron in serum containing iron-dextran, with use of sodium dithionite and alumina columns. Jacobs, J.C., Alexander, N.M. Clin. Chem. (1990) [Pubmed]
  29. Ascorbate in plasma as measured by liquid chromatography and by dichlorophenolindophenol colorimetry. VanderJagt, D.J., Garry, P.J., Hunt, W.C. Clin. Chem. (1986) [Pubmed]
  30. Aminophenylboronic acid affinity chromatography and thiobarbituric acid colorimetry compared for measuring glycated albumin. Rendell, M., Kao, G., Mecherikunnel, P., Petersen, B., Duhaney, R., Nierenberg, J., Rasbold, K., Klenk, D., Smith, P.K. Clin. Chem. (1985) [Pubmed]
  31. Cortisol production rate determined by radio gas-chromatography. Derks, H.J., Muskiet, F.A., Wolthers, B.G., Thijssen, J.H., Drayer, N.M. Clin. Chem. (1977) [Pubmed]
  32. Determinants of bumetanide response in the dog: effect of indomethacin. Smith, D.E., Lau, H.S. Journal of pharmaceutical sciences. (1983) [Pubmed]
  33. Measurement of surface color and color difference of tablet colorants by tristimulus colorimetry. Bogdansky, F.M. Journal of pharmaceutical sciences. (1975) [Pubmed]
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