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Chemical Compound Review

Betoxan     2-naphthalen-2-ylethanoic acid

Synonyms: CHEMBL948, NSC-301, N4002_ALDRICH, NSC301, SureCN238445, ...
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Disease relevance of beta-Naphthaleneacetate


High impact information on beta-Naphthaleneacetate


  1. A role for threonine 302 in the mechanism-based inactivation of P450 2B4 by 2-ethynylnaphthalene. Roberts, E.S., Pernecky, S.J., Alworth, W.L., Hollenberg, P.F. Arch. Biochem. Biophys. (1996) [Pubmed]
  2. Mechanism-based inhibition of mouse P4502b-10 by selected arylalkynes. Beebe, L.E., Roberts, E.S., Fornwald, L.W., Hollenberg, P.F., Alworth, W.L. Biochem. Pharmacol. (1996) [Pubmed]
  3. Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide. Roberts, E.S., Hopkins, N.E., Alworth, W.L., Hollenberg, P.F. Chem. Res. Toxicol. (1993) [Pubmed]
  4. Liquid chromatographic assay for the measurement of glucuronidation of arylcarboxylic acids using uridine diphospho-[U-14C] glucuronic acid. Hamar-Hansen, C., Fournel, S., Magdalou, J., Boutin, J.A., Siest, G. J. Chromatogr. (1986) [Pubmed]
  5. Studies on the metabolism of arylacetic acids. 7. The influence of varying dose size upon the conjugation pattern of 2-naphthylacetic acid in the guinea pig, mouse and hamster. Emudianughe, T.S., Caldwell, J., Smith, R.L. Xenobiotica (1987) [Pubmed]
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