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Chemical Compound Review

AG-D-35400     (2S)-2-amino-4-[[(1S)-2-(3- bromo-2,5...

Synonyms: CTK4A8949, AC1L3P2T, 114865-64-4, 2-Br-6-(Gsyl)HQ, 2-Bromo-6-(glutathion-S-yl)hydroquinone, ...
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Disease relevance of 2-Bromo-6-(monoglutathion-S-yl)hydroquinone

  • In contrast, 2-Br-3-(GSyl)HQ, 2-Br-5-(GSyl)HQ, and 2-Br-6-(GSyl)HQ caused differentially less toxicity than the diglutathionyl conjugate [1].

High impact information on 2-Bromo-6-(monoglutathion-S-yl)hydroquinone


Biological context of 2-Bromo-6-(monoglutathion-S-yl)hydroquinone


  1. 2-Bromo-(diglutathion-S-yl)hydroquinone nephrotoxicity: physiological, biochemical, and electrochemical determinants. Monks, T.J., Highet, R.J., Lau, S.S. Mol. Pharmacol. (1988) [Pubmed]
  2. The response of renal tubular epithelial cells to physiologically and chemically induced growth arrest. Jeong, J.K., Huang, Q., Lau, S.S., Monks, T.J. J. Biol. Chem. (1997) [Pubmed]
  3. Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity. Mertens, J.J., Gibson, N.W., Lau, S.S., Monks, T.J. Arch. Biochem. Biophys. (1995) [Pubmed]
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