Disease relevance of p-Methylethylbenzene

• The toxicity of 4-ethyltoluene to experimental animals was studied after single and repeated exposures [1].

High impact information on p-Methylethylbenzene

• A mutant toluene oxidase able to transform p-ethyltoluene was isolated, and a mutant strain capable of fully degrading p-ethyltoluene was constructed with a modified TOL plasmid meta-cleavage pathway able to mineralize p-ethylbenzoate [2].
• Photodissociation of jet-cooled o-, m-, and p-ethyltoluene and p-fluoroethylbenzene at both 193 and 248 nm was studied separately using vacuum ultraviolet photoionization/multimass ion imaging techniques [3].
• The results revealed that neither Farbasol nor 4-ethyltoluene induced an increased reverse mutation in bacterial cells or the formation of micronucleated polychromatic erythrocytes in bone marrow [4].

Biological context of p-Methylethylbenzene

• To study repeated-dose inhalation toxicity, male and female outbred Wistar rats were exposed in a dynamic inhalation chamber to 4-ethyltoluene vapours at concentrations of 477 or 2337 mg/m3, 6 h/day, 5 days/week for 4 weeks (20 exposure days) [1].

References