Disease relevance of tridecane

• These data coupled with absorption and toxicity studies of jet fuel HC revealed that specific HCs (tridecane and tetradecane) might be the key constituents responsible for jet fuel-induced skin irritation [1].
• No erythema was noted in 1-day in vivo HC exposures but significant erythema was observed in 4-day tridecane, tetradecane, pentadecane, and JP-8 exposed sites [1].

High impact information on tridecane

• Increasing the polycyclic cage size of NGP1-01 from a pentacycloundecane to a tridecane cage structure, but retaining the N-benzyl moiety decreased potency 10-fold, indicating a limitation on the volume of the cage that can be accommodated in the channel binding site [2].
• Permeability of the ears to hydrocortisone was monitored in vitro during tridecane- and tetradecane-induced irritation [3].
• Using the measured partition coefficient values of these n-alkanes, linear regression was used to predict tissue (except brain) and blood:air partition coefficient values for larger n-alkanes, tridecane, tetradecane, pentadecane, hexadecane, and heptadecane (n-C13 to n-C17) [4].

Analytical, diagnostic and therapeutic context of tridecane

• The resultant lines are viewed, and line widths are measured using both wetting with tridecane under a light microscope and scanning electron microscopy [5].
• Fermentations with n-tridecane substrate to produce alpha,omega-tridecanedioic acid were carried out in a 5-l bioreactor in which growth and production were separated [6].

References