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Chemical Compound Review

Hexandiol     hexane-1,1-diol

Synonyms: Hexanediol, AG-E-84610, AC1L3UBZ, CTK1A5096, 26762-52-7, ...
 
 
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Disease relevance of Hexanediol

 

High impact information on Hexanediol

  • In studying what conditions would allow only the activities of LD1 or LD1 + LD2 to be expressed in serum, we found that the respective activities could be determined by treatment with hexanediol, 0.75 mol/L and 0.55 mol/L, respectively [2].
  • Addition of hexanediol, 0.6 mol/L, to five LD isoenzyme fractions purified from human liver and heart homogenates resulted in complete loss of activities of LD4 and LD5, and partial loss of LD2 and LD3 [2].
  • Furthermore, alcohol dehydrogenase activity with hexanols or hexanediol as the substrate was found exclusively in liver cytosol [3].
  • A library of 37 soluble polycations was synthesized by oligomerization of low molecular weight oligoamines with three different crosslinkers, dithiobis-succinimidyl proprionate, dimethyl dithiobis-propionamidate, and hexanediol diacrylate [4].
  • Hexanediol diacrylate sensitization after accidental occupational exposure [5].
 

Anatomical context of Hexanediol

  • 62.5% EG and 45% HD as dentin primers were safer than 2-HEMA such as a methacrylic primer [6].

References

  1. Delayed irritation: hexanediol diacrylate and butanediol diacrylate. Malten, K.E., den Arend, J.A., Wiggers, R.E. Contact Derm. (1979) [Pubmed]
  2. Activity of lactate dehydrogenase isoenzymes LD1 and LD2 in serum as determined by using an inhibitor of the M-subunit. Tanishima, K., Hayashi, T., Matsushima, M., Mochikawa, Y. Clin. Chem. (1985) [Pubmed]
  3. Rat lung and liver microsomal cytochrome P-450 isozymes involved in the hydroxylation of n-hexane. Toftgård, R., Haaparanta, T., Eng, L., Halpert, J. Biochem. Pharmacol. (1986) [Pubmed]
  4. Degradable gene carriers based on oligomerized polyamines. Kloeckner, J., Wagner, E., Ogris, M. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2006) [Pubmed]
  5. Hexanediol diacrylate sensitization after accidental occupational exposure. Botella-Estrada, R., Mora, E., de la Cuadra, J. Contact Derm. (1992) [Pubmed]
  6. Evaluation of skin irritation and sensitization of two diol solutions used as experimental dentin primers in humans and guinea pigs. Kurihara, A., Manabe, A., Katsuno, K., Itoh, K., Hisamitsu, H., Wakumoto, S., Yoshida, T. Dental materials journal. (1996) [Pubmed]
 
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