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Chemical Compound Review: 

AMINOCARB     (4-dimethylamino-3-methyl- phenyl) N...

Synonyms: Matacil, Mitacil, Aminocarbe, Matacil 180D, SureCN119059, ...
 
 
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Disease relevance of Mitacil

 

High impact information on Mitacil

  • Historical aerial applications of the insecticide Matacil 1.8D provide an opportunity to look for potential effects of the endocrine disrupting compound 4-nonylphenol (4-NP) on Atlantic salmon (Salmo salar) populations [2].
  • The subchronic toxicity of a new formulation of Matacil (aminocarb) was assessed by exposing male and female Sprague-Dawley rats via a nose-only technique to a respirable (2.0- to 4.1-microns diameter) aerosol at chamber concentrations of 22.5, 45, and 90 micrograms of insecticide/liter of air for 2 hr/day for 30 consecutive days [1].
  • Larvae of a leptophos resistant strain of the Egyptian cotton leafworm Spodoptera littoralis (Boisd) showed varying levels of cross resistance to several organophosphorus insecticides and to the carbamate matacil [3].

References

  1. A subchronic inhalation toxicity study of a Matacil formulation in the albino rat. Breckenridge, C., Lulham, G., Hollomby, B., Bier, C., Losos, G., Ecobichon, D.J. Toxicol. Appl. Pharmacol. (1986) [Pubmed]
  2. Does an association between pesticide use and subsequent declines in catch of Atlantic salmon (Salmo salar) represent a case of endocrine disruption? Fairchild, W.L., Swansburg, E.O., Arsenault, J.T., Brown, S.B. Environ. Health Perspect. (1999) [Pubmed]
  3. Reduced sensitivity of cholinesterase as a factor of resistance in leptophos selected strain in the Egyptian cotton leafworm. Riskallah, M.R. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. (1980) [Pubmed]
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