Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

CHEMBL156672 N-hydroxynaphthalene-2- carboxamide

Synonyms: CHEBI:356773, LS-95339, DNC011660, KSC-264-28-1, AKOS000178377, ...

Lee, M.S. et al., Wang, C.Y. et al., Davis, W.L. et al., McKee, M.D. et al., Laberge, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of N,N-Naphthaloylhydroxylamine

The objective of the present study was to explore the mechanisms responsible for the strong, direct-acting mutagenicity of 2-naphthohydroxamic acid (NHA) for Salmonella typhimurium TA98 [1].

High impact information on N,N-Naphthaloylhydroxylamine

Metabolic activation of the potent mutagen, 2-naphthohydroxamic acid, in Salmonella typhimurium TA98 [1].
Horseradish peroxidase C binds a wide variety of small H-donor compounds such as benzohydroxamic acid (BHA) and 2-naphthohydroxamic acid (NHA) [2].
2-Naphthohydroxamic acid, 4-n-butoxyphenylacetohydroxamic acid, and their O-sulfonate, O-formate, O-acetate, and O-propionate derivatives were studied for cytotoxicity and sister chromatid exchange (SCE) induction in Chinese hamster ovary (CHO) cells [3].
Rat incisors were quickly dissected and immediately immersed in solutions containing the following calcium-binding reagents: arsenazo III, calmagite, murexide, N,N-naphthaloylhydroxylamine, and calcein [4].
The ultrahistochemical analysis of apical granules in the epithelial cells, i.e., granular cells, of the amphibian urinary bladder using the N,N-naphthaloylhydroxylamine procedure identified the presence of calcium in these structures [5].

References

Metabolic activation of the potent mutagen, 2-naphthohydroxamic acid, in Salmonella typhimurium TA98. Lee, M.S., Isobe, M. Cancer Res. (1990) [Pubmed]
Aromatic substrate specificity of horseradish peroxidase C studied by a combined fluorescence line narrowing/energy minimization approach: the effect of localized side-chain reorganization. Laberge, M., Osvath, S., Fidy, J. Biochemistry (2001) [Pubmed]
O-esters of N-acylhydroxylamines: toxicity and enhancement of sister-chromatid exchange in Chinese hamster ovary cells. Wang, C.Y., Garner, C.D., Lee, M.S., Shirai, T. Mutat. Res. (1981) [Pubmed]
Banding patterns in rat incisor enamel stained by histochemical complexing methods for calcium. McKee, M.D., Warshawsky, H. Anat. Rec. (1989) [Pubmed]
Histochemical and elemental localization of calcium in the granular cell subapical granules of the amphibian urinary bladder epithelium. Davis, W.L., Jones, R.G., Hagler, H.K., Farmer, G.R., Goodman, D.B. Anat. Rec. (1987) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share