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Chemical Compound Review

Coeflex     1-[2-[2-hydroxy-3-(1- piperidyl)propoxy]phe...

Synonyms: Thiokol, Thiorubber, Accralastic, GNF-PF-5152, AC1MEKKA, ...
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Disease relevance of Accralastic


High impact information on Accralastic

  • The acute toxic reaction to 14 polysulfide rubber impression materials certified by the ADA was measured after injection into the oral mucosa of two baboons for 48 h, and the inflammatory response was evaluated quantitatively [4].
  • The purpose of this study was to investigate and compare the accuracy of complete dental arch impressions and stone casts made with two kinds of impression materials (addition-type silicone and polysulfide rubber) and trays (custom tray and modified custom tray) [5].
  • Six different materials were tested: two condensation silicones, Xantopren regular (Bayer, FRG) and Xantopren light; a polyvinylsiloxane, Reprosil regular (DeTrey, Switzerland); a polysulphide Coeflex regular (Coe, USA); a polyether, Impregum (Espe, FRG); and an alginate, Cavex, Fast Set, Dust Free (Keur & Sneltjes, The Netherlands) [6].
  • If intracavitary implantation is the most desirable treatment modality for nasopharyngeal carcinoma, then the use of the polysulfide rubber as a intracavitary implant is the preferred method [7].

Analytical, diagnostic and therapeutic context of Accralastic


  1. Experimental animal models for studying antimicrobial pharmacokinetics in otitis media. Canafax, D.M., Nonomura, N., Erdmann, G.R., Le, C.T., Juhn, S.K., Giebink, G.S. Pharm. Res. (1989) [Pubmed]
  2. Allergic contact dermatitis from sealants containing polysulphide polymers (Thiokol). Wilkinson, S.M., Beck, M.H. Contact Derm. (1993) [Pubmed]
  3. Polysulfide rubber foreign body: report of a case. Gettleman, L., Agranat, B.J. Quintessence international. (1976) [Pubmed]
  4. Acute tissue irritation of polysulfide rubber impression materials. Spranley, T.J., Gettleman, L., Zimmerman, K.L. J. Dent. Res. (1983) [Pubmed]
  5. Accuracy of complete dental arch impressions and stone casts using a three-dimensional measurement system. Effects on accuracy of rubber impression materials and trays. Ishida, K. Dentistry in Japan. (1990) [Pubmed]
  6. A modified technique to determine the tear energy of impression materials. Vrijhoef, M.M., Lourens, F.L., Leydekkersgovers, G.F. Journal of oral rehabilitation. (1986) [Pubmed]
  7. Revised technique for intracavitary radiation of the nasopharynx. Saunders, T.R. The Journal of prosthetic dentistry. (1980) [Pubmed]
  8. Papulo-vesicular count for the rating of allergic patch test reactions. A simple technique based on polysulfide rubber replica. Peters, K., Serup, J. Acta Derm. Venereol. (1987) [Pubmed]
  9. Mandibular complete denture impressions with fluid wax or polysulfide rubber: a comparative study. Firtell, D.N., Koumjian, J.H. The Journal of prosthetic dentistry. (1992) [Pubmed]
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