Chemical Compound Review:
Etotoina 3-ethyl-5-phenyl- imidazolidine-2,4-dione
Synonyms:
Peganone, ethotoin, Accenon, Ethotoine, Pegoanone, ...
- Cleft lip and palate with the anticonvulsant ethotoin. Zablen, M., Brand, N. N. Engl. J. Med. (1977)
- Hydantoin-induced teratogenesis: are arene oxide intermediates really responsible? Finnell, R.H., DiLiberti, J.H. Helvetica paediatrica acta. (1983)
- Clinical pharmacology of mephenytoin and ethotoin. Troupin, A.S., Friel, P., Lovely, M.P., Wilensky, A.J. Ann. Neurol. (1979)
- Role of microtubule assembly in phenytoin teratogenic action in the sea urchin (Arbacia punctulata) embryo. Estus, S., Blumer, J.L. Mol. Pharmacol. (1989)
- Ethotoin in seizures of childhood and adolescence. Carter, C.A., Helms, R.A., Boehm, R. Neurology (1984)
- Nonlinear ethotoin kinetics. Meyer, M.C., Holcombe, B.J., Burckart, G.J., Raghow, G., Yau, M.K. Clin. Pharmacol. Ther. (1983)
- Adjunctive therapy for intractable epilepsy with ethotoin. Biton, V., Gates, J.R., Ritter, F.J., Loewenson, R.B. Epilepsia (1990)
- Enantioselective pharmacokinetics of ethotoin in humans following single oral doses of the racemate. Hooper, W.D., O'Shea, N.J., Qing, M.S. Chirality. (1992)
- Simultaneous rapid HPLC determination of anticonvulsant drugs in plasma and correlation with EMIT. Rydzewski, R.S., Gadsden, R.H., Phelps, C.A. Ann. Clin. Lab. Sci. (1980)
- Stereoselective analysis of the enantiomers of ethotoin in human serum using chiral stationary phase liquid chromatography and gas chromatography-mass spectrometry. Inotsume, N., Fujii, J., Honda, M., Nakano, M., Higashi, A., Matsuda, I. J. Chromatogr. (1988)