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Chemical Compound Review

AC1LCK1Y     9-[3,4-dihydroxy-5- (hydroxymethyl)oxolan-2...

Synonyms: 2140-67-2, N2,N2-Dimethylguanosine, Guanosine, N,N-dimethyl-
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Disease relevance of N2,N2-Dimethylguanosine


High impact information on N2,N2-Dimethylguanosine


Biological context of N2,N2-Dimethylguanosine


Anatomical context of N2,N2-Dimethylguanosine


  1. Serum levels of N2, N2-dimethylguanosine and pseudouridine as determined by radioimmunoassay for patients with malignancy. Levine, L., Waalkes, T.P., Stolbach, L. J. Natl. Cancer Inst. (1975) [Pubmed]
  2. Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. Ellis, S.R., Morales, M.J., Li, J.M., Hopper, A.K., Martin, N.C. J. Biol. Chem. (1986) [Pubmed]
  3. Reversed-phase high-performance liquid chromatographic investigation of mucosal nucleosides and bases and urinary modified nucleosides of gastrointestinal cancer patients. Nakano, K., Shindo, K., Yasaka, T., Yamamoto, H. J. Chromatogr. (1985) [Pubmed]
  4. N2,N2-dimethylguanosine-specific tRNA methyltransferase contains both nuclear and mitochondrial targeting signals in Saccharomyces cerevisiae. Li, J.M., Hopper, A.K., Martin, N.C. J. Cell Biol. (1989) [Pubmed]
  5. Location of N2,N2-dimethylguanosine-specific tRNA methyltransferase. Rose, A.M., Belford, H.G., Shen, W.C., Greer, C.L., Hopper, A.K., Martin, N.C. Biochimie (1995) [Pubmed]
  6. How single genes provide tRNA processing enzymes to mitochondria, nuclei and the cytosol. Martin, N.C., Hopper, A.K. Biochimie (1994) [Pubmed]
  7. Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Rose, A.M., Joyce, P.B., Hopper, A.K., Martin, N.C. Mol. Cell. Biol. (1992) [Pubmed]
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