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Chemical Compound Review:

ACMC-1BS9F butane-1,4-dithiol

Synonyms: ANW-17281, NSC-60198, KST-1B0060, AC1L2WRP, AC1Q7GPH, ...

Watkins, D. et al., Zanella, R. et al., Karty, J.M. et al., Lenzen, S. et al.

Zanella, Basiuk, Santiago, Basiuk, Mireles, Puente-Lee, Saniger,

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High impact information on NSC 60198

Gas-phase acidities (deltaGo(acid)) have been measured for 1,2-ethanedithiol, 1,3-propanedithiol, and 1,4-butanedithiol, using a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer [1].
Only 1,3-dimercaptopropane, 1,4-dimercaptobutane, 1,4-dithioerythritol, and 1,4-DTT, with intermediate spacing between the SH groups, reversed the inhibition of glucokinase induced by alloxan [2].
Pretreatment of the slices with 2,3-dimercaptopropanol (BAL) or 1,4-dimercaptobutane (DMB) before treatment with alloxan completely protected them against this action of alloxan, whereas 1,5-dimercaptopentane (DMP) and 1,6-dimercaptohexane (DMH) partially protected and 1,8-dimercapto-octane (DMO) had no effect [3].
Gold nanoparticles were deposited on the surface of multiwalled carbon nanotubes (MWNTs) functionalized with aliphatic bifunctional thiols (1,4-butanedithiol, 1,6-hexanedithiol, 1,8-octanedithiol, and 2-aminoethanethiol) through a direct solvent-free procedure [4].

References

The RS-.HSR Hydrogen Bond: acidities of alpha,omega-dithiols and electron affinities of their monoradicals. Karty, J.M., Wu, Y., Brauman, J.I. J. Am. Chem. Soc. (2001) [Pubmed]
Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme. Lenzen, S., Freytag, S., Panten, U. Mol. Pharmacol. (1988) [Pubmed]
Effect of alloxan on islet tissue permeability: protection and reversal by dithiols. Watkins, D., Cooperstein, S.J. J. Pharmacol. Exp. Ther. (1976) [Pubmed]
Deposition of gold nanoparticles onto thiol-functionalized multiwalled carbon nanotubes. Zanella, R., Basiuk, E.V., Santiago, P., Basiuk, V.A., Mireles, E., Puente-Lee, I., Saniger, J.M. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2005) [Pubmed]

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