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Chemical Compound Review:

Safari methyl2-[[4-dimethylamino-6- (2,2,2...

Synonyms: Upbeet, SureCN55457, AG-D-55663, ACMC-20ms17, AC-18026, ...

Abkowitz, J.L. et al., Abkowitz, J.L. et al., Abkowitz, J.L. et al., Abkowitz, J.L. et al., Kadoi, K. et al., et al.

Abkowitz, Taboada, Shelton, Catlin, Guttorp, Kiklevich,

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Disease relevance of Safari

A Streptococcus mutans Safari [1]!
The majority of lions and tigers in a Safari park in Japan were suffering from acute vesicular disease caused by a calicivirus infection [2].

High impact information on Safari

In crossover coculture studies, T-cells from Safari cats with PRCA had no inhibitory effect on colony growth from normal or autologous PRCA marrow cells [3].
To study the behavior of hematopoietic stem cells in vivo, we transplanted glucose-6-phosphate dehydrogenase (G6PD) heterozygous (female Safari) cats with small amounts of autologous marrow [4].
Fair dinkum way-out woop-woop: the Sydney to Darwin Motor Safari 1990. Part 1 [5].
Experimental data of bone marrow samples from Safari cats provides evidence for the clonal succession hypothesis of early haematopoiesis [6].

Analytical, diagnostic and therapeutic context of Safari

Predicted outcomes from simulated experiments were compared with data obtained in autologous marrow transplantation studies of glucose 6-phosphate dehydrogenase (G6PD) heterozygous female Safari cats [7].
We report similar findings in longitudinal studies of female Safari cats and demonstrate that the excessive skewing that develops with aging results from a third mechanism that has no pathologic consequence, hemizygous selection [8].

References

A Streptococcus mutans Safari! Bratthall, D. J. Dent. Res. (1997) [Pubmed]
Antibody response of lions inoculated with inactivated calicivirus vaccine experimentally prepared. Kadoi, K., Kiryu, M., Inaba, Y. New Microbiol. (1998) [Pubmed]
Lymphocytes and antibody in retrovirus-induced feline pure red cell aplasia. Abkowitz, J.L., Ott, R.L., Holly, R.D., Adamson, J.W. J. Natl. Cancer Inst. (1987) [Pubmed]
Behavior of hematopoietic stem cells in a large animal. Abkowitz, J.L., Persik, M.T., Shelton, G.H., Ott, R.L., Kiklevich, J.V., Catlin, S.N., Guttorp, P. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
Fair dinkum way-out woop-woop: the Sydney to Darwin Motor Safari 1990. Part 1. Hardy, P.H. Journal of the Royal Naval Medical Service. (1991) [Pubmed]
A stochastic model for haematopoiesis in cats. Guttorp, P., Newton, M.A., Abkowitz, J.L. IMA journal of mathematics applied in medicine and biology. (1990) [Pubmed]
Evidence that hematopoiesis may be a stochastic process in vivo. Abkowitz, J.L., Catlin, S.N., Guttorp, P. Nat. Med. (1996) [Pubmed]
An X chromosome gene regulates hematopoietic stem cell kinetics. Abkowitz, J.L., Taboada, M., Shelton, G.H., Catlin, S.N., Guttorp, P., Kiklevich, J.V. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]

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