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Chemical Compound Review

NITRIC ACID     nitric acid

Synonyms: Nital, RFNA, Salpetersaure, Salpetersaeure, HONO2, ...
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Disease relevance of nitric acid

  • Immune cell infiltration and broncovascular remodeling after nitric Acid nasal instillation in a mouse bronchiolitis obliterans model [1].

High impact information on nitric acid

  • NAC administration increased the ReGSH (P = 0.036) and decreased the MDA, MPO, and NN (P = 0.008, P = 0.01, P = 0.032, respectively), compared with the CLP group [2].
  • Nitric acid treatment results in an increase in adsorption capacity of fly ash (2.4 x 10(-5) mol/g) while it decreases the adsorption capacity for red mud (3.2 x 10(-6) mol/g) [3].
  • Nitric acid passivation does not affect in vitro biocompatibility of titanium [4].
  • Nitric acid is found mostly in particulate form, but gas to particulate partitioning of SO2 shows seasonal variation [5].
  • Nitric acid was used to extract the metals from the tissues for analysis by inductively-coupled plasma/atomic emission spectroscopy (ICP/AES) [6].

Biological context of nitric acid


Anatomical context of nitric acid

  • Animals were sacrificed following the last injection and radii were fixed in 10% NBF, decalcified in 3% Nitric acid, doubly embedded, sectioned at 4 to 5 micrometer, and routinely processed for histological measurements of the midcoronal height and width of the cartilage zones of the proximal and distal epiphyses [8].

Analytical, diagnostic and therapeutic context of nitric acid

  • Nitric acid-soluble lead in 1100 samples collected at a total of 19 monitoring stations was determined by atomic absorption spectroscopy and by differential pulse polarography [9].
  • Nitric acid digests of blood samples from pups 10 and 21 d old and from animals allowed a Pb-free period of 3-3.5 mo after treatment were also analyzed for Pb concentration [10].


  1. Immune cell infiltration and broncovascular remodeling after nitric Acid nasal instillation in a mouse bronchiolitis obliterans model. Garippo, A.L., Parra, E.R., Teodoro, W.R., Veloza, A.P., Yoshinari, N.H., Capelozzi, V.L. Lung (2006) [Pubmed]
  2. N-acetylcysteine protects the rats against phrenic nerve dysfunction in sepsis. Atis, S., Nayci, A., Ozge, A., Comelekoglu, U., Gunes, S., Bagdatoglu, O. Shock (2006) [Pubmed]
  3. Removal of dyes from aqueous solution using fly ash and red mud. Wang, S., Boyjoo, Y., Choueib, A., Zhu, Z.H. Water Res. (2005) [Pubmed]
  4. Nitric acid passivation does not affect in vitro biocompatibility of titanium. Faria, A.C., Beloti, M.M., Rosa, A.L. The International journal of oral & maxillofacial implants. (2003) [Pubmed]
  5. Gaseous and particulate air pollutants in the Northeastern Mediterranean Coast. Erduran, M.S., Tuncel, S.G. Sci. Total Environ. (2001) [Pubmed]
  6. Heavy metals in the tissues of common dolphins (Delphinus delphis) stranded on the Portuguese coast. Zhou, J.L., Salvador, S.M., Liu, Y.P., Sequeira, M. Sci. Total Environ. (2001) [Pubmed]
  7. Effects of nitric acid on carbachol reactivity of the airways in normal and allergic sheep. Abraham, W.M., Kim, C.S., King, M.M., Oliver, W., Yerger, L. Arch. Environ. Health (1982) [Pubmed]
  8. Responses of articular and epiphyseal cartilage zones of developing avian radii to estrone treatment and a 2-G environment. Negulesco, J.A., Kossler, T. Aviation, space, and environmental medicine. (1978) [Pubmed]
  9. Airborne lead in the Springfield, Missouri, area during a 19-year period (1975-1993). Sheets, R.W., Thielmann, V.J., Wallace, B.N., Lang, B.M., Collins, E.W. Environ. Pollut. (1997) [Pubmed]
  10. Tissue distribution of lead in rat pups nourished by lead-poisoned mothers. Hejtmancik, M.R., Dawson, E.B., Williams, B.J. Journal of toxicology and environmental health. (1982) [Pubmed]
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