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Chemical Compound Review:

Freon FT 1,1,1-trichloro-2,2,2- trifluoro-ethane

Synonyms: T-WD602, CFC-113a, ACMC-1CFA4, AG-E-83564, AG-F-22764, ...

Meager, A. et al., Rasmussen, K. et al., May, D.C. et al., Bloom, T.F. et al., Chu, K.C. et al.

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Disease relevance of Freon FT

Glycoprotein material extracted from human KB cells with a flurocarbon, trichlorotrifluoroethane (Arklone P), into a waste-soluble fraction binds to fibre, a structural protein of the adenovirus type-5 capsid [1].
Among 23 cleaners from one factory, all at the time using fluorocarbon 113, we found 3 persons with symptoms and signs of psychoorganic syndrome after heavy exposure to fluorocarbon 113 for 2 1/2-4 1/2 years [2].

High impact information on Freon FT

This study reports two occupational deaths resulting from exposure to fluorocarbon-113 (1,1,2-trichloro-1,2,2-trifluoroethane; FC-113) in enclosed and confined spaces [3].
Evaluation of exposures to fluorocarbon 113 in a horizontal and a vertical laminar airflow clean room [4].

Analytical, diagnostic and therapeutic context of Freon FT

Improved MR images of arterial specimens by submersion in trichlorotrifluoroethane [5].

References

Interactions of KB-cell glycoproteins with an adenovirus capsid protein. Meager, A., Butters, T.D., Mautner, V., Hughes, R.C. Eur. J. Biochem. (1976) [Pubmed]
Psychoorganic syndrome from exposure to fluorocarbon 113--an occupational disease? Rasmussen, K., Jeppesen, H.J., Arlien-Søborg, P. Eur. Neurol. (1988) [Pubmed]
A report of occupational deaths attributed to fluorocarbon-113. May, D.C., Blotzer, M.J. Arch. Environ. Health (1984) [Pubmed]
Evaluation of exposures to fluorocarbon 113 in a horizontal and a vertical laminar airflow clean room. Bloom, T.F., Egeland, G.M. American Industrial Hygiene Association journal. (1999) [Pubmed]
Improved MR images of arterial specimens by submersion in trichlorotrifluoroethane. Chu, K.C., Martin, A.J., Rutt, B.K. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. (1996) [Pubmed]

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