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Chemical Compound Review:

Apetinil N-ethyl-1-phenyl-propan-2- amine

Synonyms: Etilamfetamina, Etilamfetamine, Etilanfetamina, CHEMBL276443, SureCN162316, ...

Matsushima, K. et al., Harvey, B.R. et al., Peters, F.T. et al., Delbeke, F.T. et al., Woolverton, W.L. et al., et al.

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High impact information on d-N-Ethylamphetamine

meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships [1].
An anti-methamphetamine scFv was cloned from hybridoma cells, expressed in bacteria and its affinity towards methamphetamine and N-ethylamphetamine (ethamphetamine) was determined by Surface Plasmon Resonance (SPR) [2].
The classical stimulants amphetamine, methamphetamine, ethylamphetamine and the amphetamine-derived designer drugs MDA, MDMA ('ecstasy'), MDEA, BDB and MBDB have been widely abused for a relatively long time [3].
Some cross reactivity was observed with PBA, N-methyl-PBA N-ethylamphetamine, and N-ethyl-PBA when analyzed using a series of commercial amphetamine and methamphetamine immunoassays [4].
In the self-administration procedure, d-amphetamine (A), d-N-methylamphetamine (NMA), and d-N-ethylamphetamine (NEA) were self-administered above saline levels at two or more doses by all animals [5].

Analytical, diagnostic and therapeutic context of d-N-Ethylamphetamine

Analysis of time-lapse changes of d- and l-enantiomers of racemic ethylamphetamine and stereoselective metabolism in rat urine by HPLC determination [6].
The urinary excretion of etilamfetamine (ethylamphetamine) and its major metabolite amphetamine in humans was followed over a period of several days after the oral administration of two formulations [7].
Characterization of optical activity and simultaneous analysis of racemic ethylamphetamine (EAMP) and its metabolites, as well as the urinary excretion of the optical isomers, were examined in rats by high-performance liquid chromatography (HPLC) [8].

References

meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships. Tessel, R.E., Woods, J.H. J. Pharmacol. Exp. Ther. (1978) [Pubmed]
Engineering of recombinant antibody fragments to methamphetamine by anchored periplasmic expression. Harvey, B.R., Shanafelt, A.B., Baburina, I., Hui, R., Vitone, S., Iverson, B.L., Georgiou, G. J. Immunol. Methods (2006) [Pubmed]
Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry. Peters, F.T., Schaefer, S., Staack, R.F., Kraemer, T., Maurer, H.H. Journal of mass spectrometry : JMS. (2003) [Pubmed]
Isomeric amphetamines--a problem for urinalysis? Smith, F.P., Kidwell, D.A. Forensic Sci. Int. (1991) [Pubmed]
Structure-activity relationships among some d-N-alkylated amphetamines. Woolverton, W.L., Shybut, G., Johanson, C.E. Pharmacol. Biochem. Behav. (1980) [Pubmed]
Analysis of time-lapse changes of d- and l-enantiomers of racemic ethylamphetamine and stereoselective metabolism in rat urine by HPLC determination. Nagai, T., Kamiyama, S., Matsushima, K. Journal of analytical toxicology. (1995) [Pubmed]
The influence of diuretics on the excretion and metabolism of doping agents. III. Etilamfetamine. Delbeke, F.T., Debackere, M. Arzneimittel-Forschung. (1986) [Pubmed]
Urinary output changes in racemic ethylamphetamine and optical activity discrimination in rat urine by HPLC analysis. Matsushima, K., Nagai, T., Kanaya, H., Kato, Y., Takahashi, M., Kamiyama, S. Nippon Hoigaku Zasshi (1998) [Pubmed]

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