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Gene Review

pcaK  -  benzoate transport

Pseudomonas putida KT2440

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High impact information on pcaK


Biological context of pcaK

  • The third gene, pcaK, encodes a transporter for 4-hydroxybenzoate, and this protein is also required for chemotaxis to aromatic acids [4].
  • Primer extension analysis and lacZ fusions showed that pcaK and pcaF, which are adjacent on the chromosome, are transcribed independently [3].

Associations of pcaK with chemical compounds

  • In addition, whole cells of P. putida pcaK mutants accumulated 4-hydroxybenzoate at reduced rates compared with that in wild-type cells [4].
  • In contrast, the pcaK mutant grew at wild-type rates on benzoate [2].

Other interactions of pcaK

  • It was postulated that the reduction of pobA activation in pcaR::Tn5 mutants was because there was no expression of the pcaK gene encoding the PHB transport protein resulting in lower levels of PHB present inside the cell [5].


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