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Gene Review

SEMA6C  -  sema domain, transmembrane domain (TM),...

Homo sapiens

Synonyms: KIAA1869, SEMAY, Sema Y, Semaphorin-6C, Semaphorin-Y, ...
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Disease relevance of SEMA6C

  • The extracellular domain of SEMA6C inhibited axonal extension of nerve growth factor-differentiated PC12 cells and induced the growth cone collapse of chicken dorsal root ganglion, rat hippocampal neurons, and rat cortical neurons in a dose-responsive manner [1].

High impact information on SEMA6C


Biological context of SEMA6C


  1. Identification, characterization, and functional study of the two novel human members of the semaphorin gene family. Qu, X., Wei, H., Zhai, Y., Que, H., Chen, Q., Tang, F., Wu, Y., Xing, G., Zhu, Y., Liu, S., Fan, M., He, F. J. Biol. Chem. (2002) [Pubmed]
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