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Gene Review:

Esa4 - esterase A4

Mus musculus

Synonyms: Es-17, Es17

Otto, J. et al., Antonucci, T.K. et al.

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High impact information on Es17

Exceptions to the preferred association of alleles of Es-17 and Ups have been found in three feral populations and one inbred strain [1].
This study provides the first estimate of the distances between Es-17, Ups and Alp-1 [1].
Genetic variation of a new codominantly inherited esterase, designated ES-17, has been discovered in the house mouse using isoelectric focusing in polyacrylamide gels [2].
ES-17 was shown to be controlled by the structural locus Es-17, located on chromosome 9 [2].
The ES-17 A phenotype (three bands; isoelectric points, between pH 5.55 and pH 5.90) was found in C57BL/10Sn [2].

Anatomical context of Es17

ES-17 was present in all tissues examined, except for hemolysate and serum, and was most clearly expressed in the small intestine [2].

References

Conserved linkage within a 4-cM region of mouse chromosome 9 and human chromosome 11. Antonucci, T.K., Von Deimling, O.H., Rosenblum, B.B., Skow, L.C., Meisler, M.H. Genetics (1984) [Pubmed]
Esterase-17 (ES-17): characterization and genetic location on chromosome 9 of a bis-p-nitrophenyl phosphate-resistant esterase of the house mouse (Mus musculus). Otto, J., von Deimling, O.H. Biochem. Genet. (1983) [Pubmed]

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