Gene Review:
Apoa1 - apolipoprotein A-I
Mus musculus
Synonyms:
Alp-1, Apo-AI, ApoA-I, Apoa-1, Apolipoprotein A-I, ...
Goto,
Mottino,
Sacco,
Cushley,
Sekikawa,
Marta Ramirez Gaite,
Navab,
Buga,
Hedrick,
Fogelman,
Frank,
Anantharamaiah,
Gianazza,
Caligari,
Hakhamian,
Lusis,
Takahashi,
Parolini,
Van Lenten,
Hendizadeh,
Hama,
Ignarro,
Okon,
Sirtori,
Reddy,
Navab,
Fogelman,
Rubin,
Gregory Martin Benson,
Castellani,
Frank,
Zhu,
Forte,
Suto,
Chiesa,
Marcel,
Tillisch,
- Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice reduces atherogenesis in response to a high fat-high cholesterol diet. Baroukh, N., Ostos, M.A., Vergnes, L., Recalde, D., Staels, B., Fruchart, J., Ochoa, A., Castro, G., Zakin, M.M. FEBS Lett. (2001)
- ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice. Voyiaziakis, E., Goldberg, I.J., Plump, A.S., Rubin, E.M., Breslow, J.L., Huang, L.S. J. Lipid Res. (1998)
- Role of apolipoprotein A-I in protecting against endotoxin toxicity. Ma, J., Liao, X.L., Lou, B., Wu, M.P. Acta Biochim. Biophys. Sin. (Shanghai) (2004)
- Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Ou, J., Wang, J., Xu, H., Ou, Z., Sorci-Thomas, M.G., Jones, D.W., Signorino, P., Densmore, J.C., Kaul, S., Oldham, K.T., Pritchard, K.A. Circ. Res. (2005)
- Heteronuclear NMR studies of human serum apolipoprotein A-I. Part I. Secondary structure in lipid-mimetic solution. Okon, M., Frank, P.G., Marcel, Y.L., Cushley, R.J. FEBS Lett. (2002)
- A novel endothelial-derived lipase that modulates HDL metabolism. Jaye, M., Lynch, K.J., Krawiec, J., Marchadier, D., Maugeais, C., Doan, K., South, V., Amin, D., Perrone, M., Rader, D.J. Nat. Genet. (1999)
- High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Yuhanna, I.S., Zhu, Y., Cox, B.E., Hahner, L.D., Osborne-Lawrence, S., Lu, P., Marcel, Y.L., Anderson, R.G., Mendelsohn, M.E., Hobbs, H.H., Shaul, P.W. Nat. Med. (2001)
- Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice. Prochazka, M., Leiter, E.H., Serreze, D.V., Coleman, D.L. Science (1987)
- Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element. Claudel, T., Sturm, E., Duez, H., Torra, I.P., Sirvent, A., Kosykh, V., Fruchart, J.C., Dallongeville, J., Hum, D.W., Kuipers, F., Staels, B. J. Clin. Invest. (2002)
- Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor. Gardès, C., Blum, D., Bleicher, K., Chaput, E., Ebeling, M., Hartman, P., Handschin, C., Richter, H., Benson, G.M. J. Lipid. Res. (2011)
- Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. Castellani, L.W., Navab, M., Van Lenten, B.J., Hedrick, C.C., Hama, S.Y., Goto, A.M., Fogelman, A.M., Lusis, A.J. J. Clin. Invest. (1997)
- Beneficial effects of ApoA-I on LPS-induced acute lung injury and endotoxemia in mice. Yan, Y.J., Li, Y., Lou, B., Wu, M.P. Life Sci. (2006)
- Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J x RR F2 mice. Suto, J., Takahashi, Y., Sekikawa, K. Biochem. Genet. (2004)
- Characterization of the mouse apolipoprotein Apoa-1/Apoc-3 gene locus: genomic, mRNA, and protein sequences with comparisons to other species. Januzzi, J.L., Azrolan, N., O'Connell, A., Aalto-Setälä, K., Breslow, J.L. Genomics (1992)
- Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence. Stoffel, W., Müller, R., Binczek, E., Hofmann, K. Biol. Chem. Hoppe-Seyler (1992)
- Point mutations in apolipoprotein A-I mimic the phenotype observed in patients with classical lecithin:cholesterol acyltransferase deficiency. Chroni, A., Duka, A., Kan, H.Y., Liu, T., Zannis, V.I. Biochemistry (2005)
- ApoA-I lipidation in primary mouse hepatocytes. Separate controls for phospholipid and cholesterol transfers. Zheng, H., Kiss, R.S., Franklin, V., Wang, M.D., Haidar, B., Marcel, Y.L. J. Biol. Chem. (2005)
- Hydroxytyrosol administration enhances atherosclerotic lesion development in apo e deficient mice. Acín, S., Navarro, M.A., Arbonés-Mainar, J.M., Guillén, N., Sarría, A.J., Carnicer, R., Surra, J.C., Orman, I., Segovia, J.C., Torre, R.d.e. .L., Covas, M.I., Fernández-Bolaños, J., Ruiz-Gutiérrez, V., Osada, J. J. Biochem. (2006)
- Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I. Williamson, R., Lee, D., Hagaman, J., Maeda, N. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL. Okuhira, K., Tsujita, M., Yamauchi, Y., Abe-Dohmae, S., Kato, K., Handa, T., Yokoyama, S. J. Lipid Res. (2004)
- Apolipoprotein A-I induces translocation of protein kinase C[alpha] to a cytosolic lipid-protein particle in astrocytes. Ito, J., Li, H., Nagayasu, Y., Kheirollah, A., Yokoyama, S. J. Lipid Res. (2004)
- Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice. Li, H., Reddick, R.L., Maeda, N. Arterioscler. Thromb. (1993)
- Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production. Plump, A.S., Erickson, S.K., Weng, W., Partin, J.S., Breslow, J.L., Williams, D.L. J. Clin. Invest. (1996)
- High doses of bifendate elevate serum and hepatic triglyceride levels in rabbits and mice: animal models of acute hypertriglyceridemia. Pan, S.Y., Yang, R., Han, Y.F., Dong, H., Feng, X.D., Li, N., Geng, W., Ko, K.M. Acta Pharmacol. Sin. (2006)
- The role of apolipoprotein A-I-containing lipoproteins in atherosclerosis. Forte, T.M., McCall, M.R. Curr. Opin. Lipidol. (1994)
- In vivo regulation of apolipoprotein A-I gene expression by estradiol and testosterone occurs by different mechanisms in inbred strains of mice. Tang, J.J., Srivastava, R.A., Krul, E.S., Baumann, D., Pfleger, B.A., Kitchens, R.T., Schonfeld, G. J. Lipid Res. (1991)
- Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI. Jolley, C.D., Dietschy, J.M., Turley, S.D. Hepatology (2000)
- Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks. Prochazka, M., Serreze, D.V., Worthen, S.M., Leiter, E.H. Diabetes (1989)
- ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes. Sahoo, D., Trischuk, T.C., Chan, T., Drover, V.A., Ho, S., Chimini, G., Agellon, L.B., Agnihotri, R., Francis, G.A., Lehner, R. J. Lipid Res. (2004)
- Conserved linkage within a 4-cM region of mouse chromosome 9 and human chromosome 11. Antonucci, T.K., Von Deimling, O.H., Rosenblum, B.B., Skow, L.C., Meisler, M.H. Genetics (1984)
- D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet. Buga, G.M., Frank, J.S., Mottino, G.A., Hendizadeh, M., Hakhamian, A., Tillisch, J.H., Reddy, S.T., Navab, M., Anantharamaiah, G.M., Ignarro, L.J., Fogelman, A.M. J. Lipid Res. (2006)
- Targeted replacement of mouse apolipoprotein A-I with human ApoA-I or the mutant ApoA-IMilano. Evidence of APOA-IM impaired hepatic secretion. Parolini, C., Chiesa, G., Zhu, Y., Forte, T., Caligari, S., Gianazza, E., Sacco, M.G., Sirtori, C.R., Rubin, E.M. J. Biol. Chem. (2003)
- Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. Valenta, D.T., Ogier, N., Bradshaw, G., Black, A.S., Bonnet, D.J., Lagrost, L., Curtiss, L.K., Desrumaux, C.M. Arterioscler. Thromb. Vasc. Biol. (2006)
- Immunochemical characterization of six monoclonal antibodies to human apolipoprotein A-I: epitope mapping and expression. Marcovina, S., Fantappie, S., Zoppo, A., Franceschini, G., Catapano, A.L. J. Lipid Res. (1990)
- Epitope mapping of the human biliary amphipathic, anionic polypeptide: similarity with a calcium-binding protein isolated from gallstones and bile, and immunologic cross-reactivity with apolipoprotein A-I. Domingo, N., Grosclaude, J., Bekaert, E.D., Mège, D., Chapman, M.J., Shimizu, S., Ayrault-Jarrier, M., Ostrow, J.D., Lafont, H. J. Lipid Res. (1992)