Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

RAB31 - RAB31, member RAS oncogene family

Homo sapiens

Synonyms: RAB22B, Rab22B, Ras-related protein Rab-22B, Ras-related protein Rab-31

Bao, X. et al., Lodhi, I.J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of RAB31

Northern blots for Rab31 and Rab32 identified 4.4 kb and 1.35 kb mRNA species, respectively, in some human tissues and in human erythroleukemia (HEL) cells [1].

High impact information on RAB31

Binding of [(35)S]GTP[S] was optimal with 5 microm Mg(2+)(free) and was markedly inhibited by higher Mg(2+) concentrations in the case of GST-Rab31 but not GST-Rab32 [1].
Gapex-5, a Rab31 Guanine Nucleotide Exchange Factor that Regulates Glut4 Trafficking in Adipocytes [2].
The VPS9 domain is a guanine nucleotide exchange factor for Rab31, a Rab5 subfamily GTPase implicated in trans-Golgi network (TGN)-to-endosome trafficking [2].

Analytical, diagnostic and therapeutic context of RAB31

Molecular cloning, bacterial expression and properties of Rab31 and Rab32 [1].

References

Molecular cloning, bacterial expression and properties of Rab31 and Rab32. Bao, X., Faris, A.E., Jang, E.K., Haslam, R.J. Eur. J. Biochem. (2002) [Pubmed]
Gapex-5, a Rab31 Guanine Nucleotide Exchange Factor that Regulates Glut4 Trafficking in Adipocytes. Lodhi, I.J., Chiang, S.H., Chang, L., Vollenweider, D., Watson, R.T., Inoue, M., Pessin, J.E., Saltiel, A.R. Cell metabolism (2007) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

RAB31	Bos taurus
RAB31	Canis lupus familiaris
rab31	Danio rerio
RAB31	Gallus gallus
RAB31	Macaca mulatta
Rab31	Mus musculus
RAB31	Pan troglodytes
Rab31	Rattus norvegicus
rab31	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.