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Gene Review

Cyp2g1  -  cytochrome P450, family 2, subfamily g,...

Mus musculus

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Disease relevance of Cyp2g1

  • However, the LNG was protected from AP (at 400 mg/kg) toxicity in the Cyp2g1-null mice [1].

High impact information on Cyp2g1


Biological context of Cyp2g1


Other interactions of Cyp2g1

  • Unexpectedly, a significant reduction in the expression of the Cyp2a5 gene was found in the liver, the lateral nasal gland (LNG), and, to a lesser extent, the kidney of adult Cyp2g1-null mice [1].


  1. Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression. Zhuo, X., Gu, J., Behr, M.J., Swiatek, P.J., Cui, H., Zhang, Q.Y., Xie, Y., Collins, D.N., Ding, X. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  2. Mouse cyp2g1 gene: promoter structure and tissue-specific expression of a cyp2g1-lacz fusion gene in transgenic mice. Zhuo, X., Schwob, J.E., Swiatek, P.J., Ding, X. Arch. Biochem. Biophys. (2001) [Pubmed]
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