The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

DHX36  -  DEAH (Asp-Glu-Ala-His) box polypeptide 36

Homo sapiens

Synonyms: ATP-dependent RNA helicase DHX36, DDX36, DEAH box protein 36, G4-resolvase 1, G4R1, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of DHX36


High impact information on DHX36


Biological context of DHX36


Anatomical context of DHX36

  • Northern blotting of DDX36 shows a single strong signal of 3.8 kb in the hybridization pattern in human testis but no or very weak signal in other tissues [3].

Analytical, diagnostic and therapeutic context of DHX36

  • The DHX36 gene product was identified by mass spectrometric sequencing of a tryptic digest from the protein band on SDS-PAGE associated with activity [1].


  1. The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. Vaughn, J.P., Creacy, S.D., Routh, E.D., Joyner-Butt, C., Jenkins, G.S., Pauli, S., Nagamine, Y., Akman, S.A. J. Biol. Chem. (2005) [Pubmed]
  2. Expression research for human DDX36 and mouse Ddx36 gene in the adult testis. Fu, J.J., Li, L.Y., Liu, S.F., Xing, X.W., Liu, G., Lu, G.X. Yi Chuan Xue Bao (2003) [Pubmed]
  3. Molecular cloning and characterization of human DDX36 and mouse Ddx36 genes, new members of the DEAD/H box superfamily. Fu, J.J., Li, L.Y., Lu, G.X. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (2002) [Pubmed]
WikiGenes - Universities