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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

hsp-60  -  Protein HSP-60

Caenorhabditis elegans

 
 
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Disease relevance of hsp-60

 

High impact information on hsp-60

  • Northern blot analysis shows that unlike the evolutionarily related Hsp60 chaperonin genes, tcp-1 is not upregulated at elevated temperatures, but instead appears to be down-regulated [2].
  • Peptide mass mapping with MALDI-TOF mass spectrometry (MS) identified 10 desiccation-response proteins, among which several are known to be stress responsive including heat shock protein 60, coenzyme q biosynthesis protein, inositol monophosphatase and fumarate lyase that were found in both stresses [3].
  • We investigated the hsp70 response in resident and transplanted isopods of the species Oniscus asellus and Porcellio scaber and the hsp60 response in transplanted nematodes of the species Plectus acuminatus in six field sites along the metal gradient [4].

References

  1. Tunga penetrans: molecular identification of Wolbachia endobacteria and their recognition by antibodies against proteins of endobacteria from filarial parasites. Fischer, P., Schmetz, C., Bandi, C., Bonow, I., Mand, S., Fischer, K., Büttner, D.W. Exp. Parasitol. (2002) [Pubmed]
  2. Molecular analysis of Caenorhabditis elegans tcp-1, a gene encoding a chaperonin protein. Leroux, M.R., Candido, E.P. Gene (1995) [Pubmed]
  3. Proteomic analysis of the entomopathogenic nematode Steinernema feltiae IS-6 IJs under evaporative and osmotic stresses. Chen, S., Glazer, I., Gollop, N., Cash, P., Argo, E., Innes, A., Stewart, E., Davidson, I., Wilson, M.J. Mol. Biochem. Parasitol. (2006) [Pubmed]
  4. Stress proteins (hsp70, hsp60) induced in isopods and nematodes by field exposure to metals in a gradient near Avonmouth, UK. Arts, M.J., Schill, R.O., Knigge, T., Eckwert, H., Kammenga, J.E., Köhler, H.R. Ecotoxicology (2004) [Pubmed]
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