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MeSH Review

Dirofilaria

 
 
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Disease relevance of Dirofilaria

 

High impact information on Dirofilaria

  • An ERp60-like protein from the filarial parasite Dirofilaria immitis has both transglutaminase and protein disulfide isomerase activity [5].
  • Fourteen beagles infected with larvae (microfilariae) of Dirofilaria immitis, were randomly selected from another study in which the toxic effects of subfilaricidal doses of diethylcarbamazine were being evaluated [6].
  • Dirofilaria immitis polyproteins (DiAgs) are found as 15-kDa monomeric and 30-kDa dimeric forms in excretory-secretory products of the adult worm [7].
  • An rxr/usp homolog from the parasitic nematode, Dirofilaria immitis [8].
  • Purification and partial characterization of a transglutaminase from dog filarial parasite, Dirofilaria immitis [9].
 

Chemical compound and disease context of Dirofilaria

 

Biological context of Dirofilaria

 

Anatomical context of Dirofilaria

 

Associations of Dirofilaria with chemical compounds

 

Gene context of Dirofilaria

  • The factors that regulate interleukin-4 (IL-4)-induced IgE synthesis in helminthic infection were analysed by using an excretory-secretory component (ESC) of Dirofilaria immitis (DI) [27].
  • Studies aimed at developing immunization strategies against Dirofilaria immitis infection in dogs have shown that protection against larval challenge is of the Th2 type and that several proteins are recognized by immunized or infected animals [2].
  • A lambda gt11 cDNA recombinant that encodes Dirofilaria immitis paramyosin [28].
  • Identification and characterization of an aromatic amino acid decarboxylase from the filarial nematode, Dirofilaria immitis [29].
  • Acid phosphatase activity demonstrated in the nematodes, Dirofilaria immitis and Angiostrongylus cantonensis with special reference to the characters and distribution [30].
 

Analytical, diagnostic and therapeutic context of Dirofilaria

References

  1. Filarial paramyosin: cDNA sequences from Dirofilaria immitis and Onchocerca volvulus. Limberger, R.J., McReynolds, L.A. Mol. Biochem. Parasitol. (1990) [Pubmed]
  2. Th1 response in BALB/c mice immunized with Dirofilaria immitis soluble antigens: a possible role for Wolbachia? Marcos-Atxutegi, C., Kramer, L.H., Fernandez, I., Simoncini, L., Genchi, M., Prieto, G., Simón, F. Vet. Parasitol. (2003) [Pubmed]
  3. Dirofilaria immitis: diethylcarbamazine-induced anaphylactoid reactions in infected dogs. Hamilton, R.G., Wagner, E., April, M., Winkelstein, J.A., Sobotka, A.K., Bleeker, E., Adkinson, N.F. Exp. Parasitol. (1986) [Pubmed]
  4. Levamisole resinate as a Dirofilaria immitis microfilaricide in dogs. Bradley, R.E. J. Am. Vet. Med. Assoc. (1976) [Pubmed]
  5. An ERp60-like protein from the filarial parasite Dirofilaria immitis has both transglutaminase and protein disulfide isomerase activity. Chandrashekar, R., Tsuji, N., Morales, T., Ozols, V., Mehta, K. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  6. Dirofilaria immitis. 5. Immunopathology of filarial nephropathy in dogs. Abramowsky, C.R., Powers, K.G., Aikawa, M., Swinehart, G. Am. J. Pathol. (1981) [Pubmed]
  7. Various types of Dirofilaria immitis polyproteins selectively induce a Th2-Type immune response. Tezuka, H., Imai, S., Hidano, S., Tsukidate, S., Fujita, K. Infect. Immun. (2003) [Pubmed]
  8. An rxr/usp homolog from the parasitic nematode, Dirofilaria immitis. Shea, C., Hough, D., Xiao, J., Tzertzinis, G., Maina, C.V. Gene (2004) [Pubmed]
  9. Purification and partial characterization of a transglutaminase from dog filarial parasite, Dirofilaria immitis. Singh, R.N., Chandrashekar, R., Mehta, K. Int. J. Biochem. Cell Biol. (1995) [Pubmed]
  10. Inhibition of NADP-linked malic enzyme from Onchocerca volvulus and Dirofilaria immitis by suramin. Walter, R.D., Albiez, E.J. Mol. Biochem. Parasitol. (1981) [Pubmed]
  11. Cloning and characterization of cDNAs encoding beta-tubulin from Dirofilaria immitis and Onchocerca volvulus. Geary, T.G., Nulf, S.C., Alexander-Bowman, S.J., Mahmoud, B.M., Prichard, R.K., Klein, R.D. J. Parasitol. (1998) [Pubmed]
  12. Preliminary results on the effect of tetracycline on the embryogenesis and symbiotic bacteria (Wolbachia) of Dirofilaria immitis. An update and discussion. Genchi, C., Sacchi, L., Bandi, C., Venco, L. Parassitologia (1998) [Pubmed]
  13. Effects of tetracycline on the filarial worms Brugia pahangi and Dirofilaria immitis and their bacterial endosymbionts Wolbachia. Bandi, C., McCall, J.W., Genchi, C., Corona, S., Venco, L., Sacchi, L. Int. J. Parasitol. (1999) [Pubmed]
  14. Preparation of a highly purified allergen from Dirofilaria immitis. Reaginic antibody formation in mice. Fujita, K., Tsukidate, S. Immunology (1981) [Pubmed]
  15. Molecular cloning, expression and enzymatic activity of a thioredoxin peroxidase from Dirofilaria immitis. Klimowski, L., Chandrashekar, R., Tripp, C.A. Mol. Biochem. Parasitol. (1997) [Pubmed]
  16. Effects of treatment with ticlopidine in heartworm-negative, heartworm-infected, and embolized heartworm-infected dogs. Boudreaux, M.K., Dillon, A.R., Sartin, E.A., Ravis, W.R., Spano, J.S. Am. J. Vet. Res. (1991) [Pubmed]
  17. Detection of filaria-specific IgG4 antibodies and filarial DNA, for the screening of blood spots for Brugia timori. Fischer, P., Bonow, I., Supali, T., Rückert, P., Rahmah, N. Ann. Trop. Med. Parasitol. (2005) [Pubmed]
  18. Leukotriene C4 synthesis catalyzed by Dirofilaria immitis glutathione S-transferase. Weller, P.F., Longworth, D.L., Jaffe, J.J. Am. J. Trop. Med. Hyg. (1989) [Pubmed]
  19. Increased rat alveolar macrophage expression of functional iNOS induced by a Dirofilaria immitis immunoglobulin superfamily protein. Andrade, M.A., Siles-Lucas, M., Pérez Arellano, J.L., Pou Barreto, C., Valladares, B., Espinoza, E., Muro, A. Nitric Oxide (2005) [Pubmed]
  20. Effect of acetylsalicylic acid on vascular damage and myointimal proliferation in canine pulmonary arteries subjected to chronic injury by Dirofilaria immitis. Schaub, R.G., Keith, J.C., Rawlings, C.A. Am. J. Vet. Res. (1983) [Pubmed]
  21. Hemocyte monophenol oxidase activity in mosquitoes exposed to microfilariae of Dirofilaria immitis. Li, J.Y., Tracy, J.W., Christensen, B.M. J. Parasitol. (1989) [Pubmed]
  22. Dirofilaria immitis: comparison of cytosolic and mitochondrial glutamate dehydrogenases. Turner, A.C., Lushbaugh, W.B., Hutchison, W.F. Exp. Parasitol. (1986) [Pubmed]
  23. A highly purified allergen from excretory and secretory products of Dirofilaria immitis. Fujita, K., Tsukidate, S. Int. J. Parasitol. (1984) [Pubmed]
  24. Glycosyl transferase activity in homogenates of adult Dirofilaria immitis. Comley, J.C., Jaffe, J.J., Chrin, L.R. Mol. Biochem. Parasitol. (1982) [Pubmed]
  25. Phosphofructokinase from Dirofilaria immitis: effect of fructose 2,6-bisphosphate and AMP on the non-phosphorylated and phosphorylated forms of the enzyme. Srinivasan, N.G., Rao, G.S., Harris, B.G. Mol. Biochem. Parasitol. (1990) [Pubmed]
  26. Identification of an asparagine amidohydrolase from the filarial parasite Dirofilaria immitis. Tsuji, N., Morales, T.H., Ozols, V.V., Carmody, A.B., Chandrashekar, R. Int. J. Parasitol. (1999) [Pubmed]
  27. Purified excretory-secretory component of filarial parasite enhances Fc epsilon RII/CD23 expression on human splenic B and T cells and IgE synthesis while potentiating T-helper type 2-related cytokine generation from T cells. Yamaoka, K.A., Kolb, J.P., Miyasaka, N., Inuo, G., Fujita, K. Immunology (1994) [Pubmed]
  28. A lambda gt11 cDNA recombinant that encodes Dirofilaria immitis paramyosin. Grandea, A.G., Tuyen, L.K., Asikin, N., Davis, T.B., Philipp, M., Cohen, C., McReynolds, L.A. Mol. Biochem. Parasitol. (1989) [Pubmed]
  29. Identification and characterization of an aromatic amino acid decarboxylase from the filarial nematode, Dirofilaria immitis. Tang, L., Frank, G. Biol. Chem. (2001) [Pubmed]
  30. Acid phosphatase activity demonstrated in the nematodes, Dirofilaria immitis and Angiostrongylus cantonensis with special reference to the characters and distribution. Maki, J., Yanagisawa, T. Parasitology (1980) [Pubmed]
  31. The occurrence of an adverse reaction to chloroquine in Dirofilaria immitis-infected dogs. Desowitz, R.S., Palumbo, N.E., Perri, S.F. Tropenmedizin und Parasitologie. (1983) [Pubmed]
  32. Evaluation of a 22 kDa Dirofilaria immitis antigen for the immunodiagnosis of human pulmonary dirofilariosis. Perera, L., Muro, A., Cordero, M., Villar, E., Simón, F. Trop. Med. Parasitol. (1994) [Pubmed]
  33. Evaluation of Dirofilaria immitis excretory/secretory products for seroepidemiological studies on human dirofilariosis. Santamaría, B., Cordero, M., Muro, A., Simón, F. Parasite (1995) [Pubmed]
 
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