Gene Review:
Rspo1 - R-spondin homolog (Xenopus laevis)
Mus musculus
Synonyms:
Cristin-3, Cysteine-rich and single thrombospondin domain-containing protein 3, R-spondin, R-spondin-1, Roof plate-specific spondin-1, ...
- The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Blaydon, D.C., Ishii, Y., O'toole, E.A., Unsworth, H.C., Teh, M.T., R??schendorf, F., Sinclair, C., Hopsu-Havu, V.K., Tidman, N., Moss, C., Watson, R., de Berker, D., Wajid, M., Christiano, A.M., Kelsell, D.P. Nat. Genet. (2006)
- Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate beta-Catenin-dependent Gene Expression. Nam, J.S., Turcotte, T.J., Smith, P.F., Choi, S., Yoon, J.K. J. Biol. Chem. (2006)
- R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Kamata, T., Katsube, K., Michikawa, M., Yamada, M., Takada, S., Mizusawa, H. Biochim. Biophys. Acta (2004)