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Slc16a2  -  solute carrier family 16 (monocarboxylic...

Mus musculus

Synonyms: AW105741, MCT 8, MCT8, Mct8, Monocarboxylate transporter 8, ...
 
 
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High impact information on Slc16a2

 

Anatomical context of Slc16a2

  • Iodothyronine uptake in uninjected oocytes was reduced by albumin, but the stimulation induced by MCT8 was markedly increased [1].
 

Analytical, diagnostic and therapeutic context of Slc16a2

  • RT-PCR analysis showed mRNA expression of two isoforms of proton-coupled monocarboxylate transporters, MCT1 and MCT8, in differentiated NG108-15 cells [4].

References

  1. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. Friesema, E.C., Ganguly, S., Abdalla, A., Manning Fox, J.E., Halestrap, A.P., Visser, T.J. J. Biol. Chem. (2003) [Pubmed]
  2. Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. Dumitrescu, A.M., Liao, X.H., Weiss, R.E., Millen, K., Refetoff, S. Endocrinology (2006) [Pubmed]
  3. Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation. Boelen, A., Kwakkel, J., Alkemade, A., Renckens, R., Kaptein, E., Kuiper, G., Wiersinga, W.M., Visser, T.J. Endocrinology (2005) [Pubmed]
  4. Impaired activity of volume-sensitive anion channel during lactacidosis-induced swelling in neuronally differentiated NG108-15 cells. Mori, S., Morishima, S., Takasaki, M., Okada, Y. Brain Res. (2002) [Pubmed]
 
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