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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Sned1  -  sushi, nidogen and EGF-like domains 1

Mus musculus

Synonyms: 6720455I24Rik, AI197264, AI642697, D430044C15Rik, SST3, ...
 
 
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High impact information on Sned1

  • Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein [1].
  • Furthermore, comparative expression analysis of kidney stroma markers suggests that Snep is expressed in a specific subpopulation of stromal cells and may provide environmental cues to support regular development [1].
  • Of interest, Snep transcripts are also found at sites of embryonic apoptosis [1].
  • SST-2, SST-3 and SST-4 were specific to L [2].
  • SST-3 recognises a flagellar glycoprotein of approximately 180 kDa [2].
 

Anatomical context of Sned1

  • We have identified a novel marker of kidney stroma cells, Snep (stromal nidogen extracellular matrix protein), that is additionally expressed in mesenchymal cells of other embryonic tissues and within the nervous system [1].
 

Analytical, diagnostic and therapeutic context of Sned1

References

  1. Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein. Leimeister, C., Schumacher, N., Diez, H., Gessler, M. Dev. Dyn. (2004) [Pubmed]
  2. Inhibition of macrophage invasion by monoclonal antibodies specific to Leishmania (Viannia) braziliensis promastigotes and characterisation of their antigens. Silveira, T.G., Suzuki, E., Takahashi, H.K., Straus, A.H. Int. J. Parasitol. (2001) [Pubmed]
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