Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Cstl1 - cystatin-like 1

Mus musculus

Synonyms: RCET1, RCET2, RCET3

Yoshida, K. et al., Jahnen-Dechent, W. et al., Moscinski, L.C. et al., Shoemaker, K. et al.

Jahnen-Dechent, Schinke, Trindl, Müller-Esterl, Sablitzky, Kaiser, Blessing,

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High impact information on Cstl1

The cystatin-like domains D1 and D2 of mouse fetuin are encoded by three exons each, whereas a single terminal exon encodes the carboxyl-terminal domain D3 [1].
Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T [2].
An extensive search of the protein data base reveals 30% identity over 90 amino acids with porcine cathelin, a cystatin-like cysteine proteinase inhibitor [3].

Analytical, diagnostic and therapeutic context of Cstl1

Cystatin-like domain of mouse countertrypin, a member of mammalian fetuin family, is responsible for the inhibition of trypsin. Evidence from site-directed mutagenesis [4].

References

Cloning and targeted deletion of the mouse fetuin gene. Jahnen-Dechent, W., Schinke, T., Trindl, A., Müller-Esterl, W., Sablitzky, F., Kaiser, S., Blessing, M. J. Biol. Chem. (1997) [Pubmed]
Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T. Shoemaker, K., Holloway, J.L., Whitmore, T.E., Maurer, M., Feldhaus, A.L. Gene (2000) [Pubmed]
Molecular cloning of a novel myeloid granule protein. Moscinski, L.C., Hill, B. J. Cell. Biochem. (1995) [Pubmed]
Cystatin-like domain of mouse countertrypin, a member of mammalian fetuin family, is responsible for the inhibition of trypsin. Evidence from site-directed mutagenesis. Yoshida, K., Suzuki, Y., Yamamoto, K., Sinohara, H. Biochem. Mol. Biol. Int. (1996) [Pubmed]

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