The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt

Table of contents

About

Terms

 

Gene Review: 

Cdh6  -  cadherin 6, type 2, K-cadherin

Rattus norvegicus

Synonyms: Cadherin-6, K-cadherin, Kcad, Kidney cadherin
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Cdh6

  • Cadherin-6 immunostaining was restricted to Sertoli-round spermatid and in Sertoli-elongate spermatid junctions at approximately stages XII-I [1].
  • Whereas N-cadherin, cadherin-11, and L4-positive cadherin were expressed from Postnatal Day 7 through adulthood, cadherin-6 protein was not present at Postnatal Day 7 and first appeared at Day 21 [1].
  • P-cadherin expression was absent in oocytes of follicles in later stages of development compared to K-cadherin, which was found in oocytes at all stages of folliculogenesis [2].
  • These included three renal-specific transporters (an ADH water channel, the anion transporters RST and ROAT1), a cell adhesion molecule (K-cadherin) and a kidney-specific protein upregulated in renal carcinoma (DD96) [3].
 

Anatomical context of Cdh6

  • Immunostaining showed P- and K-cadherin expression by granulosa, as well as thecal/interstitial cells, and also in oocytes of primordial follicles [2].

References

  1. Dynamic testicular adhesion junctions are immunologically unique. II. Localization of classic cadherins in rat testis. Johnson, K.J., Boekelheide, K. Biol. Reprod. (2002) [Pubmed]
  2. Expression and localization of P-, K-, and OB-cadherin in the prepubertal rat ovary. Machell, N.H., Blaschuk, O.W., Farookhi, R. Mol. Reprod. Dev. (2002) [Pubmed]
  3. Rapid isolation of tissue-specific genes from rat kidney. Hu, E., Chen, Z., Fredrickson, T.A., Spurr, N., Gentle, S., Sims, M., Zhu, Y., Halsey, W., Van Horn S, n.u.l.l., Mao, J., Sathe, G.M., Brooks, D.P. Exp. Nephrol. (2001) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities