Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

myp2 - myosin II heavy chain Myo3

Schizosaccharomyces pombe 972h-

Motegi, F. et al., Le Goff, X. et al., Motegi, F. et al.

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High impact information on myo3

A truncated Myo2 which lacks putative Cdc4-binding sites (Myo2dIQs) was able to rescue myo2 null cells, myo3 null cells, cdc4(ts) mutant cells and cdc4 null cells [1].
Two myosin-II heavy chains have been identified in fission yeast: Co-immunoprecipitation experiments indicate that rlc1p associates more strongly with myo3p than myo2p [2].
We cloned the myo3+ gene of Schizosaccharomyces pombe which encodes a type-II myosin heavy chain. myo3 null cells showed a defect in cytokinesis under certain conditions [3].

References

Molecular mechanism of myosin-II assembly at the division site in Schizosaccharomyces pombe. Motegi, F., Nakano, K., Mabuchi, I. J. Cell. Sci. (2000) [Pubmed]
The S. pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2p. Le Goff, X., Motegi, F., Salimova, E., Mabuchi, I., Simanis, V. J. Cell. Sci. (2000) [Pubmed]
Identification of Myo3, a second type-II myosin heavy chain in the fission yeast Schizosaccharomyces pombe. Motegi, F., Nakano, K., Kitayama, C., Yamamoto, M., Mabuchi, I. FEBS Lett. (1997) [Pubmed]

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AGOS_ACR068W	Ashbya gossypii ATCC 10895
MYH11	Bos taurus
MYH11	Canis lupus familiaris
myh11a	Danio rerio
MYH11	Gallus gallus
MYH11	Homo sapiens
KLLA0E11595g	Kluyveromyces lactis NRRL Y-1140
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MGG_03060	Magnaporthe oryzae 70-15
Myh11	Mus musculus
NCU00551	Neurospora crassa OR74A
MYO1	Saccharomyces cerevisiae S288c

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