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Gene Review

cdc4  -  myosin II light chain

Schizosaccharomyces pombe 972h-

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High impact information on cdc4


Biological context of cdc4

  • Deletion of cdc4 also results in a lethal terminal phenotype characterized by multinucleate, elongated cells that fail to complete cytokinesis [1].

Associations of cdc4 with chemical compounds


  1. Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokinesis. McCollum, D., Balasubramanian, M.K., Pelcher, L.E., Hemmingsen, S.M., Gould, K.L. J. Cell Biol. (1995) [Pubmed]
  2. Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe, interacts with a phosphatidylinositol 4-kinase. Desautels, M., Den Haese, J.P., Slupsky, C.M., McIntosh, L.P., Hemmingsen, S.M. J. Biol. Chem. (2001) [Pubmed]
  3. Molecular mechanism of myosin-II assembly at the division site in Schizosaccharomyces pombe. Motegi, F., Nakano, K., Mabuchi, I. J. Cell. Sci. (2000) [Pubmed]
  4. Ultrastructure and cell wall composition in cell division cycle mutants of Schizosaccharomyces pombe deficient in septum formation. Mateos, P., Domínguez, A. Antonie Van Leeuwenhoek (1991) [Pubmed]
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