Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

FGF22 - fibroblast growth factor 22

Homo sapiens

Synonyms: FGF-22, Fibroblast growth factor 22, UNQ2500/PRO5800

Nakatake, Y. et al., Katoh, Y. et al., Zhong, W. et al.

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High impact information on FGF22

Zebrafish fgf25 (186 aa) showed 39.2%, 52.9% and 45.9% total amino-acid identity with human FGF7, FGF10 and FGF22, respectively [1].
The human FGF-22 gene was localized on chromosome 19p13 [2].
By in situ hybridization, FGF-22 mRNA in the skin was found to be preferentially expressed in the inner root sheath of the hair follicle [2].

Analytical, diagnostic and therapeutic context of FGF22

FGF8 and FGF22 were detected by RT-PCR, but not by microarrays during late cleavage divisions [3].
Mouse FGF-22 mRNA was found to be preferentially expressed in the skin among the mouse adult tissues examined by Northern blotting analysis [2].

References

Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25. Katoh, Y., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle. Nakatake, Y., Hoshikawa, M., Asaki, T., Kassai, Y., Itoh, N. Biochim. Biophys. Acta (2001) [Pubmed]
FGF ligand family mRNA expression profile for mouse preimplantation embryos, early gestation human placenta, and mouse trophoblast stem cells. Zhong, W., Wang, Q.T., Sun, T., Wang, F., Liu, J., Leach, R., Johnson, A., Puscheck, E.E., Rappolee, D.A. Mol. Reprod. Dev. (2006) [Pubmed]

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