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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

AHDC1  -  AT hook, DNA binding motif, containing 1

Homo sapiens

Synonyms: AT-hook DNA-binding motif-containing protein 1, DJ159A19.3, RP1-159A19.1
 
 
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Disease relevance of AHDC1

  • The Ashkelon Hypertension Detection and Control Program (AHDC Program): a community approach to reducing cardiovascular mortality [1].
  • In this study, regular use of AHDC chewing gum was safe and effective in removing dental plaque and served as a significant complement to the daily toothbrushing regimen of children [2].
 

High impact information on AHDC1

  • ARM & HAMMER DENTAL CARE The Baking Soda Gum (AHDC) reduced dental stain by 70.8%, compared to reductions of 71.9% and 65.3%, after use of 2 experimental gum formulations [3].
  • The purpose of this human clinical study was to determine whether a commercial chewing gum containing 5% sodium bicarbonate (ARM & HAMMER DENTAL CARE The Baking Soda Gum [AHDC]) was effective in removing dental plaque when used as a supplement to regular toothbrushing by children [2].
  • Subanalysis of the data showed that the AHDC chewing gum was particularly effective on the lingual surfaces and the posterior teeth and least effective on the facial surfaces of the anterior teeth, which do not readily come into direct contact with the gum during mastication [2].
 

Analytical, diagnostic and therapeutic context of AHDC1

  • One group was instructed to chew 2 tablets of AHDC chewing gum for 20 minutes 2 times each day (after lunch and dinner) in addition to their normal toothbrushing regimen [2].

References

  1. The Ashkelon Hypertension Detection and Control Program (AHDC Program): a community approach to reducing cardiovascular mortality. Yosefy, C., Dicker, D., Viskoper, J.R., Tulchinsky, T.H., Ginsberg, G.M., Leibovitz, E., Gavish, D. Preventive medicine. (2003) [Pubmed]
  2. An evaluation of sodium bicarbonate chewing gum as a supplement to toothbrushing for removal of dental plaque from children's teeth. Kleber, C.J., Davidson, K.R., Rhoades, M.L. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) (2001) [Pubmed]
  3. Efficacy of baking soda-containing chewing gum in removing natural tooth stain. Mankodi, S.M., Conforti, N., Berkowitz, H. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) (2001) [Pubmed]
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