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Gene Review

ADCY1  -  adenylate cyclase 1 (brain)

Bos taurus

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High impact information on ADCY1


Anatomical context of ADCY1


Associations of ADCY1 with chemical compounds

  • An antibody (RM) raised against the carboxyl-terminal decapeptide of the alpha subunit of the stimulatory guanine nucleotide regulatory protein (Gs alpha) has been used to study the interaction of Gs alpha with bovine brain adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC] [7].


  1. Antisera against a guanine nucleotide binding protein from retina cross-react with the beta subunit of the adenylyl cyclase-associated guanine nucleotide binding proteins, Ns and Ni. Gierschik, P., Codina, J., Simons, C., Birnbaumer, L., Spiegel, A. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  2. GTP is not required for calmodulin stimulation of bovine brain adenylate cyclase. Heideman, W., Wierman, B.M., Storm, D.R. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  3. Resolution of adenylate cyclase sensitive and insensitive to Ca2+ and calcium-dependent regulatory protein (CDR) by CDR-sepharose affinity chromatography. Westcott, K.R., La Porte, D.C., Storm, D.R. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  4. Adenylate cyclase of human articular chondrocytes. Responsiveness to prostaglandins and other hormones. Houston, J.P., McGuire, M.K., Meats, J.E., Ebsworth, N.M., Russell, R.G., Crawford, A., Mac Neil, S. Biochem. J. (1982) [Pubmed]
  5. Interactions of fluoride and guanine nucleotides with thyroid adenylate cyclase. Goldhammer, A., Wolff, J. Biochim. Biophys. Acta (1982) [Pubmed]
  6. Inhibition of bovine adrenocortical adenylate cyclase activity by adenosine. Glynn, P., Cooper, D.M. Biochim. Biophys. Acta (1978) [Pubmed]
  7. Immunoprecipitation of adenylate cyclase with an antibody to a carboxyl-terminal peptide from Gs alpha. Morris, D., McHugh-Sutkowski, E., Moos, M., Simonds, W.F., Spiegel, A.M., Seamon, K.B. Biochemistry (1990) [Pubmed]
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