Gene Review:
Adcy1 - adenylate cyclase 1
Mus musculus
Synonyms:
AC1, ATP pyrophosphate-lyase 1, Adenylate cyclase type 1, Adenylate cyclase type I, Adenylyl cyclase 1, ...
- Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. Maas, J.W., Indacochea, R.A., Muglia, L.M., Tran, T.T., Vogt, S.K., West, T., Benz, A., Shute, A.A., Holtzman, D.M., Mennerick, S., Olney, J.W., Muglia, L.J. J. Neurosci. (2005)
- Genetic Evidence for Adenylyl Cyclase 1 as a Target for Preventing Neuronal Excitotoxicity Mediated by N-Methyl-D-aspartate Receptors. Wang, H., Gong, B., Vadakkan, K.I., Toyoda, H., Kaang, B.K., Zhuo, M. J. Biol. Chem. (2007)
- Localization of adenylyl cyclase proteins in the rodent retina. Abdel-Majid, R.M., Tremblay, F., Baldridge, W.H. Brain Res. Mol. Brain Res. (2002)
- A nucleotide regulatory site for somatostatin inhibition of adenylate cyclase in S49 lymphoma cells. Jakobs, K.H., Aktories, K., Schultz, G. Nature (1983)
- Experimental metastasis correlates with cyclic AMP accumulation in B16 melanoma clones. Sheppard, J.R., Koestler, T.P., Corwin, S.P., Buscarino, C., Doll, J., Lester, B., Greig, R.G., Poste, G. Nature (1984)
- Altered activation by calcitonin and inhibition by somatostatin of human embryonal carcinoma cell adenylate cyclase with retinoic acid-induced differentiation. Liapi, C., Anderson, W.B., Evain-Brion, D. Dev. Biol. (1986)
- Distinctive and synergistic signaling of human adenosine A2a and dopamine D2L receptors in CHO cells. Tang, Y., Demarest, K.T. J. Recept. Signal Transduct. Res. (2005)
- Depressant effect of forskolin on spontaneous locomotor activity in mice. Barraco, R.A., Phillis, J.W., Altman, H.J. Gen. Pharmacol. (1985)
- Biochemical, functional and behavioral evaluation of a series of novel antipsychotic-like agents. Von Voigtlander, P.F., Lahti, R.A., Tang, A.H., Sethy, V.H. Archives internationales de pharmacodynamie et de thérapie. (1983)
- Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex. Abdel-Majid, R.M., Leong, W.L., Schalkwyk, L.C., Smallman, D.S., Wong, S.T., Storm, D.R., Fine, A., Dobson, M.J., Guernsey, D.L., Neumann, P.E. Nat. Genet. (1998)
- Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Timpl, P., Spanagel, R., Sillaber, I., Kresse, A., Reul, J.M., Stalla, G.K., Blanquet, V., Steckler, T., Holsboer, F., Wurst, W. Nat. Genet. (1998)
- Increased expression of the c-fos proto-oncogene in bone from patients with fibrous dysplasia. Candeliere, G.A., Glorieux, F.H., Prud'homme, J., St-Arnaud, R. N. Engl. J. Med. (1995)
- Development of activatable adenylate cyclase in the preimplantation mouse embryo and a role for cyclic AMP in blastocoel formation. Manejwala, F., Kaji, E., Schultz, R.M. Cell (1986)
- Selection of a variant lymphoma cell deficient in adenylate cyclase. Bourne, H.R., Coffino, P., Tomkins, G.M. Science (1975)
- An adenylate cyclase of brain reflects propensity for breast cancer in mice. Cotzias, G.C., Tang, L.C. Science (1977)
- The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18). Guermonprez, P., Khelef, N., Blouin, E., Rieu, P., Ricciardi-Castagnoli, P., Guiso, N., Ladant, D., Leclerc, C. J. Exp. Med. (2001)
- beta-Adrenergic receptors in pediatric tumors: uncoupled beta 1-adrenergic receptor in Ewing's sarcoma. Whitsett, J.A., Burdsall, J., Workman, L., Hollinger, B., Neely, J. J. Natl. Cancer Inst. (1983)
- ETn insertion in the mouse Adcy1 gene: transcriptional and phylogenetic analyses. Leong, W.L., Dobson, M.J., Logsdon, J.M., Abdel-Majid, R.M., Schalkwyk, L.C., Guernsey, D.L., Neumann, P.E. Mamm. Genome (2000)
- Spatiotemporal localization of the calcium-stimulated adenylate cyclases, AC1 and AC8, during mouse brain development. Nicol, X., Muzerelle, A., Bachy, I., Ravary, A., Gaspar, P. J. Comp. Neurol. (2005)
- Role of efficient neurotransmitter release in barrel map development. Lu, H.C., Butts, D.A., Kaeser, P.S., She, W.C., Janz, R., Crair, M.C. J. Neurosci. (2006)
- Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation. Wang, H., Pineda, V.V., Chan, G.C., Wong, S.T., Muglia, L.J., Storm, D.R. J. Neurosci. (2003)
- Role of the calcium modulated cyclases in the development of the retinal projections. Nicol, X., Bennis, M., Ishikawa, Y., Chan, G.C., Repérant, J., Storm, D.R., Gaspar, P. Eur. J. Neurosci. (2006)
- Adenylate cyclase 1 as a key actor in the refinement of retinal projection maps. Ravary, A., Muzerelle, A., Hervé, D., Pascoli, V., Ba-Charvet, K.N., Girault, J.A., Welker, E., Gaspar, P. J. Neurosci. (2003)
- Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases. Vadakkan, K.I., Wang, H., Ko, S.W., Zastepa, E., Petrovic, M.J., Sluka, K.A., Zhuo, M. Molecular pain [electronic resource] (2006)
- ATP Stimulates Mouse Embryonic Stem Cell Proliferation via Protein Kinase C, Phosphatidylinositol 3-Kinase/Akt, and Mitogen-Activated Protein Kinase Signaling Pathways. Heo, J.S., Han, H.J. Stem Cells (2006)
- Genetic elimination of behavioral sensitization in mice lacking calmodulin-stimulated adenylyl cyclases. Wei, F., Qiu, C.S., Kim, S.J., Muglia, L., Maas, J.W., Pineda, V.V., Xu, H.M., Chen, Z.F., Storm, D.R., Muglia, L.J., Zhuo, M. Neuron (2002)
- Parathyroid hormone-related peptide as an endogenous inducer of parietal endoderm differentiation. van de Stolpe, A., Karperien, M., Löwik, C.W., Jüppner, H., Segre, G.V., Abou-Samra, A.B., de Laat, S.W., Defize, L.H. J. Cell Biol. (1993)
- Receptor-mediated internalization is critical for the inhibition of the expression of growth hormone by somatostatin in the pituitary cell line AtT-20. Sarret, P., Nouel, D., Dal Farra, C., Vincent, J.P., Beaudet, A., Mazella, J. J. Biol. Chem. (1999)
- Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. Dumuis, A., Sebben, M., Bockaert, J. Mol. Pharmacol. (1988)
- Vasoactive intestinal polypeptide receptors linked to an adenylate cyclase, and their relationship with biogenic amine- and somatostatin-sensitive adenylate cyclases on central neuronal and glial cells in primary cultures. Chneiweiss, H., Glowinski, J., Prémont, J. J. Neurochem. (1985)
- Targeted oncogenesis in the thyroid of transgenic mice. Feunteun, J., Michiels, F., Rochefort, P., Caillou, B., Talbot, M., Fournes, B., Mercken, L., Schlumberger, M., Monier, R. Horm. Res. (1997)
- Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells. Mayor, F., Benovic, J.L., Caron, M.G., Lefkowitz, R.J. J. Biol. Chem. (1987)
- Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. Diaz-Laviada, I., Larrodera, P., Nieto, J.L., Cornet, M.E., Diaz-Meco, M.T., Sanchez, M.J., Guddal, P.H., Johansen, T., Haro, A., Moscat, J. J. Biol. Chem. (1991)
- Somatostatin inhibits corticotropin-releasing factor-stimulated adrenocorticotropin release, adenylate cyclase, and activation of adenosine 3',5'-monophosphate-dependent protein kinase isoenzymes in AtT20 cells. Litvin, Y., Leiser, M., Fleischer, N., Erlichman, J. Endocrinology (1986)
- Calcium and pituitary adenylate cyclase-activating polypeptide induced expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture. Akiyama, M., Minami, Y., Nakajima, T., Moriya, T., Shibata, S. J. Neurochem. (2001)
- Pituitary adenylate cyclase-activating polypeptide induces cAMP production independently from vasoactive intestinal polypeptide in osteoblast-like cells. Suzuki, A., Kotoyori, J., Oiso, Y., Kozawa, O. Cell. Signal. (1994)
- In vitro proliferation of murine spleen cells: inhibition by monoclonal antibodies to L3T4 and Lyt-2 T cell markers or intracellular cyclic adenosine monophosphate. Zhou, P., Gorzynski, T., Dowjat, W.K., Rabin, R., Zaleski, M.B. Exp. Cell Biol. (1989)
- Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP. Wong, S.T., Athos, J., Figueroa, X.A., Pineda, V.V., Schaefer, M.L., Chavkin, C.C., Muglia, L.J., Storm, D.R. Neuron (1999)
- The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini. Watson, E.L., Jacobson, K.L., Singh, J.C., Idzerda, R., Ott, S.M., DiJulio, D.H., Wong, S.T., Storm, D.R. J. Biol. Chem. (2000)
- Requirement of adenylate cyclase 1 for the ephrin-A5-dependent retraction of exuberant retinal axons. Nicol, X., Muzerelle, A., Rio, J.P., Métin, C., Gaspar, P. J. Neurosci. (2006)
- Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects. Rohrer, D.K., Desai, K.H., Jasper, J.R., Stevens, M.E., Regula, D.P., Barsh, G.S., Bernstein, D., Kobilka, B.K. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Electroretinographic oscillatory potentials are reduced in adenylyl cyclase type I deficient mice. Tremblay, F., Abdel-Majid, R., Neumann, P.E. Vision Res. (2002)
- Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses. Li, S., Lee, M.L., Bruchas, M.R., Chan, G.C., Storm, D.R., Chavkin, C. Mol. Pharmacol. (2006)