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Gene Review:

HSPA1A - heat shock 70kDa protein 1A

Bos taurus

Synonyms: HSP70-2, HSPA1B, HSPA2

Jayasena, S.M. et al., Grosz, M.D. et al., Gallagher, D.S. et al.

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High impact information on HSPA1B

The probe for the tandemly arrayed HSP70-1 and HSP70-2 sequences mapped to bovine chromosome 23, syntenic with glyoxalase 1, 21 steroid hydroxylase, and major histocompatibility class I loci [1].
Another hsp70 gene (hsp70-1) was located further upstream, arranged in direct tandem with hsp70-2 [2].
One gene, hsp70-2, was completely sequenced and found to contain nine introns ranging in size from 78 to 195 bp [2].
Fluorescence in situ hybridization localized HSP70-2 to Chromosome (Chr) 23 band 22 (the BoLA region), HSP70-3 to Chr 10 band 34, and HSP70-4 to Chr 3 band 13 [3].

References

Syntenic conservation of HSP70 genes in cattle and humans. Grosz, M.D., Womack, J.E., Skow, L.C. Genomics (1992) [Pubmed]
Molecular characterisation of a hsp70 gene from the filarial parasite Setaria digitata. Jayasena, S.M., Chandrasekharan, N.V., Karunanayake, E.H. Int. J. Parasitol. (1999) [Pubmed]
Chromosomal localization of HSP70 genes in cattle. Gallagher, D.S., Grosz, M.D., Womack, J.E., Skow, L.C. Mamm. Genome (1993) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AT5G02490	Arabidopsis thaliana
AGOS_AER187W	Ashbya gossypii ATCC 10895
LOC102155697	Canis lupus familiaris
hsc70	Danio rerio
Hsp70Bbb	Drosophila melanogaster
Hsp68	Drosophila melanogaster
Hsp70Bc	Drosophila melanogaster
Hsp70Aa	Drosophila melanogaster
Hsp70Ab	Drosophila melanogaster
Hsp70Bb	Drosophila melanogaster
Hsp70Ba	Drosophila melanogaster
Hsc70-2	Drosophila melanogaster
HSPA1B	Homo sapiens
HSPA1A	Homo sapiens
KLLA0E20527g	Kluyveromyces lactis NRRL Y-1140
HSPA1B	Macaca mulatta
Hspa1a	Mus musculus
LOC100608888	Pan troglodytes
Hspa1a	Rattus norvegicus
Hspa1b	Rattus norvegicus
SSA3	Saccharomyces cerevisiae S288c
SSA4	Saccharomyces cerevisiae S288c
hsp70	Xenopus (Silurana) tropicalis
hspa1l	Xenopus (Silurana) tropicalis
LOC100485441	Xenopus (Silurana) tropicalis

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