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Gene Review:

SLC2A8 - solute carrier family 2 (facilitated...

Bos taurus

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High impact information on SLC2A8

Glut1, Glut3, Glut8, and SGLT-I were expressed in all stages studied [1].
Whether the culture environment was in vitro or in vivo affected the expression of glucose transporter transcripts Glut-3, Glut-4 and Glut-8 [2].
Bovine glucose transporter GLUT8: cloning, expression, and developmental regulation in mammary gland [3].
The expression of GLUT8 has been shown to depend on gonadotropin secretion in human testes and to be regulated by insulin in the blastocyst [3].
Transient transfection studies using a FLAG epitope tagged construct in COS-7 cells revealed that bovine GLUT8 is localized to the cytoplasm in non-stimulated conditions [3].

Anatomical context of SLC2A8

A 2.1-kb GLUT8 mRNA transcript was detected at high levels in bovine testes, at moderate levels in lactating bovine mammary gland, lung, kidney, spleen, intestine and skeletal muscle, and at low levels in bovine liver [3].

References

Glucose transporter expression is developmentally regulated in in vitro derived bovine preimplantation embryos. Augustin, R., Pocar, P., Navarrete-Santos, A., Wrenzycki, C., Gandolfi, F., Niemann, H., Fischer, B. Mol. Reprod. Dev. (2001) [Pubmed]
In vitro and in vivo culture effects on mRNA expression of genes involved in metabolism and apoptosis in bovine embryos. Knijn, H.M., Wrenzycki, C., Hendriksen, P.J., Vos, P.L., Zeinstra, E.C., van der Weijden, G.C., Niemann, H., Dieleman, S.J. Reprod. Fertil. Dev. (2005) [Pubmed]
Bovine glucose transporter GLUT8: cloning, expression, and developmental regulation in mammary gland. Zhao, F.Q., Miller, P.J., Wall, E.H., Zheng, Y.C., Dong, B., Neville, M.C., McFadden, T.B. Biochim. Biophys. Acta (2004) [Pubmed]

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AT1G75220	Arabidopsis thaliana
AT1G19450	Arabidopsis thaliana
SLC2A8	Canis lupus familiaris
slc2a8	Danio rerio
Tret1-2	Drosophila melanogaster
SLC2A8	Gallus gallus
SLC2A8	Homo sapiens
SLC2A8	Macaca mulatta
Slc2a8	Mus musculus
Os05g0579000	Oryza sativa Japonica Group
Os05g0567800	Oryza sativa Japonica Group
SLC2A8	Pan troglodytes
Slc2a8	Rattus norvegicus
LOC100486943	Xenopus (Silurana) tropicalis

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