The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Pmpca  -  peptidase (mitochondrial processing) alpha

Rattus norvegicus

Synonyms: Alpha-MPP, Mitochondrial-processing peptidase subunit alpha, Mppa, P-55
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Pmpca

  • Excepting the 1.2-mg diet treatment, maternal weight gains during gestation were greater for P-55 groups compared with gains of the P-115 groups, possibly reflecting maternal growth [1].
  • Both maternal weight gains and fetal weights were less for the 1.2-mg, P-55 group; otherwise reproductive performance was similar among the groups [1].
  • The wild-type and mutated beta-MPPs were co-expressed with alpha-MPP in Escherichia coli [2].

High impact information on Pmpca

  • Moreover, the acidified site of alpha-MPP, which binds to the distal basic site in the long presequence, recognized the authentic P(2) arginine as the distal site in compensation for ionic interaction at the proximal site in the mutant MPP [3].

Analytical, diagnostic and therapeutic context of Pmpca

  • The purified protease contained two protein subunits of 55 kd (P-55) and 52 kd (P-52) as determined by SDS-PAGE [4].


WikiGenes - Universities