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Gene Review

DMGDH  -  dimethylglycine dehydrogenase

Homo sapiens

Synonyms: DMGDHD, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH
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Biological context of DMGDH


Anatomical context of DMGDH


Associations of DMGDH with chemical compounds


Analytical, diagnostic and therapeutic context of DMGDH


  1. Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency. Binzak, B.A., Wevers, R.A., Moolenaar, S.H., Lee, Y.M., Hwu, W.L., Poggi-Bach, J., Engelke, U.F., Hoard, H.M., Vockley, J.G., Vockley, J. Am. J. Hum. Genet. (2001) [Pubmed]
  2. Mammalian electron transferring flavoprotein.flavoprotein dehydrogenase complexes observed by microelectrospray ionization-mass spectrometry and surface plasmon resonance. Hoard-Fruchey, H.M., Goetzman, E., Benson, L., Naylor, S., Vockley, J. J. Biol. Chem. (2004) [Pubmed]
  3. Biogenesis of the covalently flavinylated mitochondrial enzyme dimethylglycine dehydrogenase. Otto, A., Stoltz, M., Sailer, H.P., Brandsch, R. J. Biol. Chem. (1996) [Pubmed]
  4. Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study. Moolenaar, S.H., Poggi-Bach, J., Engelke, U.F., Corstiaensen, J.M., Heerschap, A., de Jong, J.G., Binzak, B.A., Vockley, J., Wevers, R.A. Clin. Chem. (1999) [Pubmed]
  5. Tissue specificity of rat mitochondrial dimethylglycine dehydrogenase expression. Lang, H., Minaian, K., Freudenberg, N., Hoffmann, R., Brandsch, R. Biochem. J. (1994) [Pubmed]
  6. Structure and analysis of the human dimethylglycine dehydrogenase gene. Binzak, B.A., Vockley, J.G., Jenkins, R.B., Vockley, J. Mol. Genet. Metab. (2000) [Pubmed]
  7. Organization of the genes involved in dimethylglycine and sarcosine degradation in Arthrobacter spp.: implications for glycine betaine catabolism. Meskys, R., Harris, R.J., Casaite, V., Basran, J., Scrutton, N.S. Eur. J. Biochem. (2001) [Pubmed]
  8. Anti-mitochondrial antibodies in patients with dilated cardiomyopathy (anti-M7) are directed against flavoenzymes with covalently bound FAD. Otto, A., Stähle, I., Klein, R., Berg, P.A., Pankuweit, S., Brandsch, R. Clin. Exp. Immunol. (1998) [Pubmed]
  9. Measurement of dimethylglycine in biological fluids. Porter, D.H., Lin, M., Wagner, C. Anal. Biochem. (1985) [Pubmed]
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