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Gene Review

ccne1  -  cyclin E1

Danio rerio

Synonyms: G1/S-specific cyclin-E1, SO:0000704, ccne, cyce, fa18e07, ...
 
 
 
 
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High impact information on ccne

  • These results suggest an additional role for cyclin E during early embryogenesis, in addition to its established role during the G1/S transition in somatic cells [1].
  • During the rapid cell cycles of the early cleavage stage, which lacks a G1 phase, the cyclin E mRNA, protein, and associated H1 kinase activity were found to be constitutive, in contrast to their reported cyclic behavior during the cycle of cultured mammalian cells [1].
  • Cyclin E mRNA was reduced during epiboly (approximately 6-8 hr postfertilization, HPF), concomitantly with a marked reduction in cell division rates [1].
 

Biological context of ccne

References

  1. Zebrafish cyclin E regulation during early embryogenesis. Yarden, A., Geiger, B. Dev. Dyn. (1996) [Pubmed]
 
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