Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

cahz - carbonic anhydrase

Danio rerio

Synonyms: CAH-Z, Carbonate dehydratase, Carbonic anhydrase, SO:0000704, cah, ...

Shiao, J.C. et al., Peterson, R.E. et al., Peterson, R.E. et al.

Peterson, Tu, Linser,

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High impact information on cahz

We have isolated a 29,000-Da carbonic anhydrase (CA) protein from the zebrafish, Danio rerio, sequenced two peptide fragments, and tentatively identified it as a high-activity CA by inhibition kinetics [1].
Ionocytes showed prominent immunostaining of carbonic anhydrase and Na(+)-K(+)-ATPase, indicating its role in transepithelial transport of HCO(3) (-) across the membranous labyrinth into the endolymph [2].
Carbonic anhydrase, which hydrolyses CO(2) and produces HCO(3) (-) and H(+), was also localized in the hair cells [2].
The expression patterns of these three markers clearly show that the Müller cells mature in stages: HNK-1 labeling and glutamine synthetase arise earlier than carbonic anhydrase expression [3].

References

Isolation and characterization of a carbonic anhydrase homologue from the zebrafish (Danio rerio). Peterson, R.E., Tu, C., Linser, P.J. J. Mol. Evol. (1997) [Pubmed]
How can teleostean inner ear hair cells maintain the proper association with the accreting otolith? Shiao, J.C., Lin, L.Y., Horng, J.L., Hwang, P.P., Kaneko, T. J. Comp. Neurol. (2005) [Pubmed]
Müller cell differentiation in the zebrafish neural retina: evidence of distinct early and late stages in cell maturation. Peterson, R.E., Fadool, J.M., McClintock, J., Linser, P.J. J. Comp. Neurol. (2001) [Pubmed]

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CA13	Bos taurus
CA13	Canis lupus familiaris
ca2	Danio rerio
CA13	Gallus gallus
CA13	Homo sapiens
CA13	Macaca mulatta
Car13	Mus musculus
CA13	Pan troglodytes
Car13	Rattus norvegicus
ca13	Xenopus (Silurana) tropicalis

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