Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Zyx - Zyxin

Drosophila melanogaster

Synonyms: BcDNA:LD06023, CG32018, DLim-1, DmLIM-1, Dmel\CG32018, ...

Renfranz, P.J. et al., Ahern-Djamali, S.M. et al.

Ahern-Djamali, Bachmann, Hua, Reddy, Kastenmeier, Walter, Hoffmann,

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High impact information on Zyx102EF

All members of this family have a conserved domain organization, bind the focal adhesion protein zyxin, and localize to focal adhesions and stress fibers [1].
Molecular and phylogenetic characterization of Zyx102, a Drosophila orthologue of the zyxin family that interacts with Drosophila Enabled [2].
Zyxin is a LIM domain protein that is found in vertebrate adherens junctions and focal adhesions [2].

Biological context of Zyx102EF

Lastly, we show that the zyx102 gene and Drosophila Ena are co-expressed during oogenesis and early embryogenesis, indicating that the two proteins may be able to interact during the development of the Drosophila egg chamber and early embryo [2].

References

Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled. Ahern-Djamali, S.M., Bachmann, C., Hua, P., Reddy, S.K., Kastenmeier, A.S., Walter, U., Hoffmann, F.M. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
Molecular and phylogenetic characterization of Zyx102, a Drosophila orthologue of the zyxin family that interacts with Drosophila Enabled. Renfranz, P.J., Siegrist, S.E., Stronach, B.E., Macalma, T., Beckerle, M.C. Gene (2003) [Pubmed]

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