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Gene Review

Lim1  -  CG11354 gene product from transcript...

Drosophila melanogaster

Synonyms: BcDNA:GH04929, CG10760, CG11354, Dlim1, Dmel\CG11354, ...
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High impact information on Lim1

  • No Lim1 misexpression occurred upon aristaless misexpression [1].
  • Proximal-distal leg development in Drosophila requires the apterous gene and the Lim1 homologue dlim1 [2].
  • Our findings show that dlim1 is an essential gene that when mutated results in lethality near the larval-pupal boundary [3].

Biological context of Lim1

  • Here we describe the isolation and characterization of another LIM homeobox gene in Drosophila termed dlim1, a homolog of the vertebrate Lim-1 gene [3].


  1. Requirements of Lim1, a Drosophila LIM-homeobox gene, for normal leg and antennal development. Tsuji, T., Sato, A., Hiratani, I., Taira, M., Saigo, K., Kojima, T. Development (2000) [Pubmed]
  2. Proximal-distal leg development in Drosophila requires the apterous gene and the Lim1 homologue dlim1. Pueyo, J.I., Galindo, M.I., Bishop, S.A., Couso, J.P. Development (2000) [Pubmed]
  3. The LIM homeodomain protein dLim1 defines a subclass of neurons within the embryonic ventral nerve cord of Drosophila. Lilly, B., O'Keefe, D.D., Thomas, J.B., Botas, J. Mech. Dev. (1999) [Pubmed]
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