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Gene Review

Fur2  -  Furin 2

Drosophila melanogaster

Synonyms: 154521_at, CG18734, CG4235, DMH#11, Dfur2, ...
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Disease relevance of Fur2

  • The cleavage of pro-vWF by Dfurin2 shows that the previously reported lack of cleavage of the precursor of the beta A-chain of activin-A by Dfurin2 in this vaccinia expression system is substrate determined [1].

High impact information on Fur2


Biological context of Fur2


Associations of Fur2 with chemical compounds


Other interactions of Fur2

  • Genes encoding seven distinct members of this family have so far been characterized in vertebrates: furin, PC2, PC1/PC3, PC4, PACE4, PC5/PC6 and PC7/PC8/LPC [5].


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