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Gene Review

OTOG  -  otogelin

Homo sapiens

Synonyms: DFNB18B, FLJ46346, MLEMP, OTGN, Otogelin, ...
 
 
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High impact information on OTOG

  • A variety of nonsensory cells located underneath these membranes could be identified as synthesizing otogelin [1].
  • Finally, this study revealed a maturation process of the tectorial membrane, as evidenced by the progressive organization of otogelin labeling into thick and spaced radial fiber-like structures [1].
  • Otogelin: a glycoprotein specific to the acellular membranes of the inner ear [1].
  • Mapping of the otogelin gene (OTGN) to mouse chromosome 7 and human chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18 [2].

References

  1. Otogelin: a glycoprotein specific to the acellular membranes of the inner ear. Cohen-Salmon, M., El-Amraoui, A., Leibovici, M., Petit, C. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  2. Mapping of the otogelin gene (OTGN) to mouse chromosome 7 and human chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18. Cohen-Salmon, M., Mattei, M.G., Petit, C. Mamm. Genome (1999) [Pubmed]
 
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